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Found 1059 with Last Name = 'tsai' and Initial = 'y'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093055(CHEMBL443796 | {2-[5-Methoxy-1-(naphthalene-1-sulf...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326392((2S)-1-({(2S,4S)-4-[2-(1,3-Dihydro-2H-isoindol-2-y...)
Affinity DataKi:  1.30nMAssay Description:Competitive inhibition of human recombinant FAP expressed in Hi5 insect cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093046(CHEMBL75734 | {2-[1-(2,5-Dimethoxy-benzenesulfonyl...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093054(CHEMBL75010 | {2-[5-Methoxy-1-(naphthalene-2-sulfo...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  2.30nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093053(CHEMBL72574 | {2-[1-(4-Chloro-benzenesulfonyl)-5-m...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093048(CHEMBL72554 | {2-[7-Methoxy-1-(naphthalene-2-sulfo...)
Affinity DataKi:  5nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093047(CHEMBL75758 | {2-[1-(2,5-Dimethoxy-benzenesulfonyl...)
Affinity DataKi:  7.40nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50326373((R)-1-(2-(1-naphthamido)acetyl)pyrrolidin-2-ylboro...)
Affinity DataKi:  7.90nMAssay Description:Competitive inhibition of human recombinant FAP expressed in Hi5 insect cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093045(CHEMBL76466 | {2-[5-Methoxy-1-(4-methoxy-benzenesu...)
Affinity DataKi:  8nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093052(CHEMBL419824 | {2-[1-(2,5-Dimethoxy-benzenesulfony...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50135653(2,4,6,8,10,12-hexa(2-chloro phenylmethyl)-2,4,6,8,...)
Affinity DataKi:  10nMAssay Description:Inhibitory activity of the compound against ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM30707(2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...)
Affinity DataKi:  16nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  23nMAssay Description:Compound was evaluated for its binding affinity for rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  38nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50135653(2,4,6,8,10,12-hexa(2-chloro phenylmethyl)-2,4,6,8,...)
Affinity DataKi:  39nMAssay Description:Inhibitory activity of the compound against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093049(CHEMBL75029 | {2-[1-(4-Chloro-benzenesulfonyl)-7-m...)
Affinity DataKi:  45nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50135654(2,4,6,8,10,12-hexa(3,5-dimethoxyphenylmethyl)-2,4,...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity of the compound against ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  78nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093051(CHEMBL74378 | {2-[7-Methoxy-1-(4-methoxy-benzenesu...)
Affinity DataKi:  93nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070947(2-ethyl-1'-methylspiro[2,3-dihydrobenzo[b]furan-3,...)
Affinity DataKi:  102nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070948(1',2-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-(...)
Affinity DataKi:  124nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  130nMAssay Description:Compound was evaluated for its binding affinity for rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50135654(2,4,6,8,10,12-hexa(3,5-dimethoxyphenylmethyl)-2,4,...)
Affinity DataKi:  130nMAssay Description:Inhibitory activity of the compound against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160665(Butyl-carbamic acid 16-hydroxy-hexadecyl ester | C...)
Affinity DataKi:  130nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160664(Butyl-carbamic acid 8-butylcarbamoyloxy-octyl este...)
Affinity DataKi:  150nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160667(Butyl-carbamic acid 14-butylcarbamoyloxy-tetradecy...)
Affinity DataKi:  160nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160659(Butyl-carbamic acid 12-butylcarbamoyloxy-dodecyl e...)
Affinity DataKi:  160nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160660(Butyl-carbamic acid 10-butylcarbamoyloxy-decyl est...)
Affinity DataKi:  160nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160661(Butyl-carbamic acid 16-butylcarbamoyloxy-hexadecyl...)
Affinity DataKi:  170nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50093050(CHEMBL306569 | {2-[1-(2,5-Dimethoxy-benzenesulfony...)
Affinity DataKi:  183nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor stably transfected to HEK 293 human embryonic kidney cells using [3H]-lysergic acid die...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160656(Butyl-carbamic acid 10-hydroxy-decyl ester | CHEMB...)
Affinity DataKi:  200nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160657(Butyl-carbamic acid 14-hydroxy-tetradecyl ester | ...)
Affinity DataKi:  200nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160666(Butyl-carbamic acid 5-butylcarbamoyloxy-pentyl est...)
Affinity DataKi:  250nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160654(Butyl-carbamic acid 12-hydroxy-dodecyl ester | CHE...)
Affinity DataKi:  300nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50135652(2,6,8N,9,11,12-hexabenzo[d][1,3]dioxol-5-ylmethyl-...)
Affinity DataKi:  310nMAssay Description:Inhibitory activity of the compound against ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50135652(2,6,8N,9,11,12-hexabenzo[d][1,3]dioxol-5-ylmethyl-...)
Affinity DataKi:  320nMAssay Description:Inhibitory activity of the compound against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160663(Butyl-carbamic acid 2-butylcarbamoyloxy-ethyl este...)
Affinity DataKi:  360nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Chung-Hsing University

Curated by ChEMBL
LigandPNGBDBM50160662(Butyl-carbamic acid 8-hydroxy-octyl ester | CHEMBL...)
Affinity DataKi:  360nMAssay Description:Inhibition constant for acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50026752(1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...)
Affinity DataKi:  451nMAssay Description:Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070946(1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...)
Affinity DataKi:  505nMAssay Description:Binding affinity against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070946(1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-...)
Affinity DataKi:  505nMAssay Description:Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  510nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  600nMAssay Description:Compound was evaluated for its binding affinity for human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  702nMAssay Description:Compound was evaluated for its binding affinity for human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt-activated lipase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKi:  800nMAssay Description:Dissociation constant of the compound (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBile salt-activated lipase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKi:  800nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetBile salt-activated lipase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKi:  800nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Homo sapiens (Human))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50070947(2-ethyl-1'-methylspiro[2,3-dihydrobenzo[b]furan-3,...)
Affinity DataKi:  853nMAssay Description:Binding affinity of the compound against Opioid receptor delta 1 was determined in brain membrane preparations from male Hartley guinea-pigsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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