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Found 64 with Last Name = 'cao' and Initial = 'zx'
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386751(CHEMBL2046884)
Affinity DataIC50:  6nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386750(CHEMBL2046699)
Affinity DataIC50:  7nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386748(CHEMBL2046726)
Affinity DataIC50:  9nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  10nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263317((S)-allyl 2-cyano-2-(3-ethyl-4-oxo-5-((4-(3-(2-(py...)
Affinity DataIC50:  23nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263318(CHEMBL477408 | allyl 2-(5-((4-acetylphenylamino)me...)
Affinity DataIC50:  34nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263587(CHEMBL477615 | propyl 2-cyano-2-(3-ethyl-5-((4-hyd...)
Affinity DataIC50:  36nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263588(CHEMBL477616 | ethyl 2-cyano-2-(3-ethyl-4-oxo-5-((...)
Affinity DataIC50:  37nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263356(5-((2-(1-cyano-2-oxo-2-(2,2,2-trifluoroethylamino)...)
Affinity DataIC50:  41nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263589(CHEMBL503480 | ethyl 2-(5-((m-toluidino)methylene)...)
Affinity DataIC50:  46nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263442(2-cyano-2-(5-((4-(2-(dimethylamino)ethoxy)phenylam...)
Affinity DataIC50:  71nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263443(2-cyano-N-(2,2-difluoroethyl)-2-(5-((4-(2-(dimethy...)
Affinity DataIC50:  74nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263643(CHEMBL476575 | ethyl 2-(5-((4-acetylphenylamino)me...)
Affinity DataIC50:  81nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263444(2-cyano-2-(3-ethyl-4-oxo-5-((4-(2-(pyrrolidin-1-yl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263445(CHEMBL476137 | ethyl 2-cyano-2-(3-ethyl-5-((2-fluo...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263644(CHEMBL476782 | N-(3-((2-(1-cyano-2-(1-(hydroxymeth...)
Affinity DataIC50:  190nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263446(2-(3-ethyl-4-oxo-5-((phenylamino)methylene)thiazol...)
Affinity DataIC50:  270nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263489(CHEMBL478654 | N-(3-(5-(2H-tetrazol-5-yl)-2-(2-(th...)
Affinity DataIC50:  330nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263645(3-((2-(1-cyano-2-(ethylamino)-2-oxoethylidene)-3-e...)
Affinity DataIC50:  345nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263646(CHEMBL475947 | N2-(pyridin-3-ylmethyl)-5-(2H-tetra...)
Affinity DataIC50:  490nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263693(CHEMBL516582 | ethyl 2-cyano-2-(3-ethyl-5-((4-(2-m...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM12107(1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole 15 | 4-(4...)
Affinity DataIC50:  530nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263490(4-((cyclopropylmethyl)(propyl)amino)-2-(1-phenylet...)
Affinity DataIC50:  550nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263491(4-(3-methoxyphenylamino)-2-(1-phenylethylamino)pyr...)
Affinity DataIC50:  580nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263492(4-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(1-phenyleth...)
Affinity DataIC50:  750nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263530(CHEMBL476145 | N4-(4-tert-butylphenyl)-N2-(pyridin...)
Affinity DataIC50:  960nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human FLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263531(CHEMBL476146 | N4-(2,3-dihydrobenzo[b][1,4]dioxin-...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263694(2-(1-phenylethylamino)-4-((tetrahydro-2H-pyran-2-y...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263695(2-(benzo[d][1,3]dioxol-5-ylmethylamino)-4-((cyclop...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263696(3-(4-hydroxybenzylidene)-1-(3-(4-hydroxybenzyliden...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263697(7-Nitro-3-oxy-5-trifluoromethyl-benzothiazole-2-ca...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human FMSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human FLT4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM8053(2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 24 | 4...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263532(4-(3-nitrophenyl)-N-(4-nitrophenyl)pyrimidin-2-ami...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human c-kitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263533(CHEMBL455343 | N-(3-(2-(4-hydroxyphenylamino)pyrim...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263698(4-[4-(3-Amino-phenyl)-pyrimidin-2-ylamino]-phenol ...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263534(4-(3-chlorophenyl)-N-(4-chlorophenyl)pyrimidin-2-a...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50263741(5-Cyano-7-nitro-3-oxy-benzothiazole-2-carboxylic a...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM8054(2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 25 | 4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM16919(3-[(2S)-2-amino-3-[(5-{thieno[2,3-c]pyridin-2-yl}p...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50386749(CHEMBL2046883)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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