Affinity DataIC50: 1nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Kit (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of c-Kit (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of PHD2 (unknown origin) by fluorescence energy transfer analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human PHD2 assesssed as hydroxylation of Pro564 in human HIF-1alpha by TR-FRET assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO—OX1 or CHO—OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair