BindingDB PrimarySearch_ki

Found 122 with Last Name = 'backos' and Initial = 'ds'

Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50105838(FENOBAM)

Ki: 32nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50105838(FENOBAM)

Ki: 33nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50450061(CHEMBL4166199)

Ki: 1.88E+3nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50450078(CHEMBL4167825)

Ki: 3.08E+3nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50450077(CHEMBL4164391)

Ki: >1.00E+4nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50450076(CHEMBL4163974)

Ki: >1.00E+4nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50450074(CHEMBL4171187)

Ki: >1.00E+4nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50450060(CHEMBL4172276)

Ki: >1.00E+4nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50450059(CHEMBL4160584)

Ki: >1.00E+4nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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Metabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Montana

Curated by ChEMBL

PNG

BDBM50450075(CHEMBL4174628)

Ki: >1.00E+4nMAssay Description:Displacement of MPEP from mGluR5 (unknown origin) after 3 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-1(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)

IC50: 3nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)

IC50: 4nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair

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3D Structure (crystal)

Ribosomal protein S6 kinase alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50111384(CHEMBL3604794)

IC50: 4nMAssay Description:Inhibition of RSK3 (unknown origin)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50111384(CHEMBL3604794)

IC50: 5nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-1(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50111384(CHEMBL3604794)

IC50: 6nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)

IC50: 13nMAssay Description:Inhibition of RSK3 (unknown origin)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-6(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)

IC50: 15nMAssay Description:Inhibition of RSK4 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assayMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568111(CHEMBL4878141 | US11851436, Compound A1-12)

IC50: 16nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564453(CHEMBL4794096)

IC50: 16nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568112(CHEMBL4851452)

IC50: 18nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568106(CHEMBL4849660 | US11851436, Compound A1-4)

IC50: 18nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)

IC50: 18nMAssay Description:Inhibition of RSK3 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assayMore data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564457(CHEMBL4800500)

IC50: 21nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)

IC50: 23nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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3D Structure (crystal)

Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)

IC50: 24nMAssay Description:Inhibition of RSK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assayMore data for this Ligand-Target Pair

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3D Structure (crystal)

Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568105(CHEMBL4858455 | US11851436, Compound A1-3)

IC50: 25nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568114(CHEMBL4857399)

IC50: 26nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Ribosomal protein S6 kinase alpha-1(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM25017(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)

IC50: 31nMAssay Description:Inhibition of RSK1 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK a substrate by [32P] gammaATP assayMore data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564458(CHEMBL4788376)

IC50: 32nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568115(CHEMBL4864190)

IC50: 35nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564448(CHEMBL4788980)

IC50: 39nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564449(CHEMBL4779166)

IC50: 49nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM4817(N-[2-(dimethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo...)

IC50: 50nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

PDB Reactome pathway
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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568104(CHEMBL4858257 | US11851436, Compound A1-2)

IC50: 56nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564459(CHEMBL4781578)

IC50: 61nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564446(CHEMBL3542344)

IC50: 61nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)

IC50: 62nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564450(CHEMBL4786972)

IC50: 65nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564447(CHEMBL4799580)

IC50: 75nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568109(CHEMBL4861235 | US11851436, Compound A1-10)

IC50: 80nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568110(CHEMBL4865383 | US11851436, Compound A1-11)

IC50: 82nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564451(CHEMBL4782796)

IC50: 83nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564454(CHEMBL4792246)

IC50: 84nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM4813(N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...)

IC50: 89nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564453(CHEMBL4794096)

IC50: 93nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

PDB Reactome pathway
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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50568113(CHEMBL4873445)

IC50: 96nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564455(CHEMBL4781062)

IC50: 97nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

PDB Reactome pathway
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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564462(CHEMBL4796639)

IC50: 101nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

PDB Reactome pathway
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5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564459(CHEMBL4781578)

IC50: 107nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL

PNG

BDBM50564461(CHEMBL4795330)

IC50: 108nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair

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Displayed 1 to 50 (of 122 total ) | Next | Last >>

Filter my 122 hits

Targets 11▿
- Ribosomal protein S6 kinase alpha-3 34
- 5'-AMP-activated protein kinase catalytic subunit alpha-1 21
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 20
- Vascular endothelial growth factor receptor 2 12
- ATP-dependent translocase ABCB1 11
- Metabotropic glutamate receptor 5 10
- Eyes absent homolog 2 [253-538] 6
- Ribosomal protein S6 kinase alpha-2 3
- Ribosomal protein S6 kinase alpha-1 3
- Bromodomain-containing protein 4 1
- Ribosomal protein S6 kinase alpha-6 1
- ...
Publications 6▿
- Eur J Med Chem 197: (2020) 53
- Bioorg Med Chem 28: (2020) 22
- Bioorg Med Chem 41: (2021) 20
- Bioorg Med Chem 25: 3223-3234 (2017) 11
- Bioorg Med Chem 26: 4797-4803 (2018) 10
- J Biol Chem 289: 16349-61 (2014) 6
Institutions 3▿
- University Of Colorado Anschutz Medical Campus 95
- University Of Montana 21
- University of Colorado School of Medicine 6
Affinity: 3 to 7.4E+5 nM▿
- Ki 10
- IC50 101
- Kd 4
- EC50 7
- Affinity ≤ nM
Xtal structures: 4
Docked structures: 0
Catalog Cmpds: 11