Compile Data Set for Download or QSAR
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Found 28 with Last Name = 'barycki' and Initial = 'r'
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50304585((20S)-1alpha,25-Dihydroxy-2-methylene-18,19-dinorv...)
Affinity DataKi:  0.0200nMAssay Description:Displacement of radiolabeled 1alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [3H]1alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50304583(1alpha,25-Dihydroxy-2-methylene-18,19,21-trinorvit...)
Affinity DataKi:  0.100nMAssay Description:Displacement of radiolabeled 1alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataKi:  0.100nMAssay Description:Displacement of radiolabeled 1alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50304584(1alpha,25-Dihydroxy-2-methylene-19,21-dinorvitamin...)
Affinity DataKi:  0.200nMAssay Description:Displacement of radiolabeled 1alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292629((23S)-25-dehydro-2-methylene-19-nor-1alpha-hydroxy...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]1alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292630((23R)-25-dehydro-2-methylene-19-nor-1alpha-hydroxy...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]1alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92780(VIMI)
Affinity DataKi:  21nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92778(AB47)
Affinity DataKi:  21nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataKi:  24nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataKi:  32nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92779(TS17)
Affinity DataKi:  39nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92781(CPA1)
Affinity DataKi:  42nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataKi:  53nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92778(AB47)
Affinity DataKi:  68nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92776(24COOH-25(OH)D3)
Affinity DataKi:  90nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92780(VIMI)
Affinity DataKi:  90nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataKi:  92nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92779(TS17)
Affinity DataKi:  1.52E+3nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92776(24COOH-25(OH)D3)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM92781(CPA1)
Affinity DataKi:  3.34E+3nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50304583(1alpha,25-Dihydroxy-2-methylene-18,19,21-trinorvit...)
Affinity DataEC50:  0.0600nMAssay Description:Activity at VDR in rat osteosarcoma cells assessed as induction of 24-hydroxylase reporter gene transcription by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  0.300nMAssay Description:Activity at VDR in rat osteosarcoma cells assessed as induction of 24-hydroxylase reporter gene transcription by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  0.200nMAssay Description:Activity at rat recombinant full length VDR expressed in rat ROS 17/2.8 cells transfected with 24-hydroxylase gene promoter assessed as transcription...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292630((23R)-25-dehydro-2-methylene-19-nor-1alpha-hydroxy...)
Affinity DataEC50:  100nMAssay Description:Activity at rat recombinant full length VDR expressed in rat ROS 17/2.8 cells transfected with 24-hydroxylase gene promoter assessed as transcription...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50304584(1alpha,25-Dihydroxy-2-methylene-19,21-dinorvitamin...)
Affinity DataEC50:  0.200nMAssay Description:Activity at VDR in rat osteosarcoma cells assessed as induction of 24-hydroxylase reporter gene transcription by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50304585((20S)-1alpha,25-Dihydroxy-2-methylene-18,19-dinorv...)
Affinity DataEC50:  0.0200nMAssay Description:Activity at VDR in rat osteosarcoma cells assessed as induction of 24-hydroxylase reporter gene transcription by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Rattus norvegicus)
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50292629((23S)-25-dehydro-2-methylene-19-nor-1alpha-hydroxy...)
Affinity DataEC50:  2nMAssay Description:Activity at rat recombinant full length VDR expressed in rat ROS 17/2.8 cells transfected with 24-hydroxylase gene promoter assessed as transcription...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed