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Found 3 Enz. Inhib. hit(s) with Target = '1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial' and Ligand = 'BDBM8610'
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataKi:  24nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataKi:  32nMAssay Description:Inhibition assay using CYP24A1 and CYP27B1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University of Wisconsin

LigandPNGBDBM8610(1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imi...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CYP24A1 expressed in Chinese hamster V79 cells using [3H-1beta]-1alpha,25(OH)2D3 as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed