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Found 300 with Last Name = 'casas' and Initial = 'j'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataKi:  50nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341324(CHEMBL1766482 | rel-(1R,2S,4R,5S)-6-[[1-Undecyl-1H...)
Affinity DataKi:  50nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318564((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)
Affinity DataKi:  60nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318563((1R,2S,3r,4R,5S,6s)-6-[(1-Tetradecyl-1H-1,2,3-tria...)
Affinity DataKi:  80nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318562((1R,2S,3r,4R,5S,6s)-6-[(1-Decyl-1H-1,2,3-triazol-4...)
Affinity DataKi:  90nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341335(CHEMBL1766474 | rel-(1R,2S,4R,5S)-6-[[1-(4-Cyclohe...)
Affinity DataKi:  290nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)
Affinity DataKi:  300nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318560(CHEMBL1083795 | N-decylaminocyclitol)
Affinity DataKi:  300nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318560(CHEMBL1083795 | N-decylaminocyclitol)
Affinity DataKi:  300nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318561((1R,2S,3r,4R,5S,6s)-6-[(1-Nonyl-1H-1,2,3-triazol-4...)
Affinity DataKi:  330nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341333(CHEMBL1766470 | rel-(1R,2S,4R,5S)-6-[[1-(3,3-Diphe...)
Affinity DataKi:  770nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569050(CHEMBL4848172)
Affinity DataKi:  800nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341331(CHEMBL1766489 | rel-(1R,2S,4R,5S)-6-[[1-(10-Hydrox...)
Affinity DataKi:  890nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341334(CHEMBL1766473 | rel-(1R,2S,4R,5S)-6-[(1-Adamantyl-...)
Affinity DataKi:  1.05E+3nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318559((1R,2S,3r,4R,5S,6s)-6-[(1-Octyl-1H-1,2,3-triazol-4...)
Affinity DataKi:  1.80E+3nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569051(CHEMBL4865548)
Affinity DataKi:  2.00E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318558((1R,2S,3r,4R,5S,6s)-6-((1-(6-propoxyhexyl)-1H-1,2,...)
Affinity DataKi:  2.40E+3nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase C(Bacillus cereus)
Institute Of Advance Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50332109(CHEMBL1287861 | Tert-butyl 1-(benzyloxy[3-(dimethy...)
Affinity DataKi:  2.50E+3nMAssay Description:Non-competitive inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase C(Bacillus cereus)
Institute Of Advance Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50332115(3-(N-(benzyloxy)-2-(tert-butyloxycarbonylamino)dod...)
Affinity DataKi:  2.50E+3nMAssay Description:Mixed-type inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569048(CHEMBL4861323)
Affinity DataKi:  3.60E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Rattus norvegicus)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50187501(CHEMBL3827445)
Affinity DataKi:  5.00E+3nMAssay Description:Competitive inhibition of rat liver microsomal S1PL using varying levels of [3-3H]-D(+) erythro-sphinganine-1-phosphate as substrate incubated for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Rattus norvegicus)
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50187501(CHEMBL3827445)
Affinity DataKi:  5.00E+3nMAssay Description:Competitive inhibition of rat S1PL in presence of D(+)-erythro-sphinganine-1-phosphate measured after 15 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569049(CHEMBL4878103)
Affinity DataKi:  5.40E+3nMAssay Description:Non-competitive inhibition of recombinant ASAH2 stably over expressed in human A-375 cell lysate using RBM14C24 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558370(CHEMBL4784427)
Affinity DataKi:  5.60E+3nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558364(CHEMBL4754006)
Affinity DataKi:  6.30E+3nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318557((1R,2S,3r,4R,5S,6s)-6-(3-(1-decyl-1H-1,2,3-triazol...)
Affinity DataKi:  7.60E+3nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558371(CHEMBL4763050)
Affinity DataKi:  9.10E+3nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase C(Bacillus cereus)
Institute Of Advance Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50332105(1-(hydroxy(2-(trimethylammonio)ethyl)amino)-1-oxod...)
Affinity DataKi:  1.20E+4nMAssay Description:Uncompetitive inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558367(CHEMBL4754871)
Affinity DataKi:  1.64E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558368(CHEMBL4748268)
Affinity DataKi:  1.75E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558365(CHEMBL4756827)
Affinity DataKi:  1.90E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318556((1R,2S,3r,4R,5S,6s)-6-[(1-Phenethyl-1H-1,2,3-triaz...)
Affinity DataKi:  1.91E+4nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318554((1R,2S,3r,4R,5S,6s)-6-(3-(1-octyl-1H-1,2,3-triazol...)
Affinity DataKi:  1.99E+4nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318555((1R,2S,3r,4R,5S,6s)-6-[2-(1-Undecyl-1H-1,2,3-triaz...)
Affinity DataKi:  2.02E+4nMpH: 5.2Assay Description:Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558369(CHEMBL4791053)
Affinity DataKi:  2.04E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlkaline ceramidase 3(Mus musculus)
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569048(CHEMBL4861323)
Affinity DataKi:  2.55E+4nMAssay Description:Non-competitive inhibition of ACER3 in ASAH2-null mouse embryonic fibroblast lysate using RBM14C16 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase C(Bacillus cereus)
Institute Of Advance Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50332119(1-(hydroxy[3-(trimethylammonio)propyl]amino)-1-oxo...)
Affinity DataKi:  2.60E+4nMAssay Description:Mixed-type inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline ceramidase 3(Mus musculus)
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569049(CHEMBL4878103)
Affinity DataKi:  3.44E+4nMAssay Description:Non-competitive inhibition of ACER3 in ASAH2-null mouse embryonic fibroblast lysate using RBM14C16 as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Spanish National Research Council (Csic)

Curated by ChEMBL
LigandPNGBDBM50558366(CHEMBL4763487)
Affinity DataKi:  3.67E+4nMAssay Description:Competitive inhibition of human S1PL using varying levels of RBM13 as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)

Curated by ChEMBL
LigandPNGBDBM50569052(CHEMBL4866400)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human ASAH2 using RBM14C24 fluorogenic substrate measured at pH 7.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586222(CHEMBL5082786)
Affinity DataIC50:  20nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318564((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)
Affinity DataIC50:  30nMpH: 5.2Assay Description:Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318564((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)
Affinity DataIC50:  30.2nMAssay Description:Inhibition of recombinant beta-glucocerebrosidase after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataIC50:  50nMpH: 5.2Assay Description:Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 5.2 after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341324(CHEMBL1766482 | rel-(1R,2S,4R,5S)-6-[[1-Undecyl-1H...)
Affinity DataIC50:  60nMpH: 5.2Assay Description:Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 5.2 after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341332(CHEMBL1766350 | rel-(1R,2S,4R,5S)-6-[(1-(3,5-Bis(b...)
Affinity DataIC50:  60nMpH: 7.4Assay Description:Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 7.4 after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50318564((1R,2S,3r,4R,5S,6s)-6-((1-dodecyl-1H-1,2,3-triazol...)
Affinity DataIC50:  60nMpH: 7.4Assay Description:Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586222(CHEMBL5082786)
Affinity DataIC50:  71nMAssay Description:Inhibition of BRD2-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50586230(CHEMBL5081350)
Affinity DataIC50:  72nMAssay Description:Inhibition of BRD3-BD2 (unknown origin) incubated for 6 hrs by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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