Affinity DataKi: 22nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 77nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 127nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 144nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 177nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 817nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 857nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.08E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.17E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.27E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.34E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.71E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.24E+3nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.96E+3nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membrane by competitive displacement assayMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against on human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against on human calpain 1More data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 48.7nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration tested against neuronal nitric oxide synthase (nNOS ) from rat cerebellumMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 55.4nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 75.9nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration tested against neuronal nitric oxide synthase (nNOS ) from rat cerebellumMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibitory activity against on calpain in C6 glial cellsMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 85.5nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 88.6nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration tested against neuronal nitric oxide synthase (nNOS ) from rat cerebellumMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration tested against neuronal nitric oxide synthase (nNOS ) from rat cerebellumMore data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of isolated human calpain1More data for this Ligand-Target Pair
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Institut Henri Beaufour
Curated by ChEMBL
Institut Henri Beaufour
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Inhibitory activity against on human calpain 1More data for this Ligand-Target Pair