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Found 37 with Last Name = 'chen' and Initial = 'yr'
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50438750(CHEMBL2414884)
Affinity DataKi:  71nMAssay Description:Competitive inhibition of human beta-glucocerebrosidase by Lineweaver-Burk double reciprocal plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50438754(CHEMBL2414880)
Affinity DataKi:  400nMAssay Description:Competitive inhibition of human beta-glucocerebrosidase by Lineweaver-Burk double reciprocal plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50438752(CHEMBL2414882)
Affinity DataKi:  400nMAssay Description:Competitive inhibition of human beta-glucocerebrosidase by Lineweaver-Burk double reciprocal plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50438753(CHEMBL2414881)
Affinity DataKi:  1.00E+3nMAssay Description:Competitive inhibition of human beta-glucocerebrosidase by Lineweaver-Burk double reciprocal plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50438748(CHEMBL2414879)
Affinity DataKi:  1.10E+3nMAssay Description:Non-competitive inhibition of human beta-glucocerebrosidase by Lineweaver-Burk double reciprocal plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)
Affinity DataKi:  1.30E+3nMAssay Description:Competitive inhibition of human beta-glucocerebrosidase by Lineweaver-Burk double reciprocal plot methodMore data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50438751(CHEMBL2414883)
Affinity DataKi:  3.20E+3nMAssay Description:Competitive inhibition of human beta-glucocerebrosidase by Lineweaver-Burk double reciprocal plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50438749(CHEMBL2414888)
Affinity DataKi:  4.10E+3nMAssay Description:Competitive inhibition of human beta-glucocerebrosidase by Lineweaver-Burk double reciprocal plot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330230(1-(4-(((1S)-2-Hydroxy-1-phenylethyl)amino)-5,6,7,8...)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330238((E)-4-(Diethylamino)-1-(4-(((1R)-2-hydroxy-1-pheny...)
Affinity DataIC50:  9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330242((E)-4-(Dimethylamino)-1-(4-[(1S)-1-phenylpropyl]am...)
Affinity DataIC50:  12nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330241((E)-4-(Dimethylamino)-1-(4-[(1R)-1-phenylethyl]ami...)
Affinity DataIC50:  12nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330234(1-(4-[(1R)-1-Phenylethyl]amino-5,6,7,8-tetrahydrop...)
Affinity DataIC50:  20nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330239((E)-1-(4-[(1R)-2-Hydroxy-1-phenylethyl]amino-5,6,7...)
Affinity DataIC50:  21nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330235(1-(4-[(1R)-1-Phenylpropyl]amino-5,6,7,8-tetrahydro...)
Affinity DataIC50:  46nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330237((E)-4-(Dimethylamino)-1-(4-[(1S)-2-hydroxy-1-pheny...)
Affinity DataIC50:  70nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330240((E)-1-(4-[(1S)-2-Hydroxy-1-phenylethyl]amino-5,6,7...)
Affinity DataIC50:  89nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330232((2S)-2-Phenyl-2-[7-(vinylsulfonyl)-5,6,7,8-tetrahy...)
Affinity DataIC50:  91nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330243((E)-1-(4-[(1R)-1-Benzyl-2-hydroxyethyl]amino-5,6,7...)
Affinity DataIC50:  149nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50:  223nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330224((2S)-2-Phenyl-2-(5,6,7,8-tetrahydrobenzo[4,5]thien...)
Affinity DataIC50:  720nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330228((2S)-2-(6,7-Dihydro-5H-cyclopenta[4,5]thieno[2,3-d...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330231(1-(4-[(1S)-2-Hydroxy-1-phenylethyl]amino-5,6,7,8-t...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330233(1-(4-[(1R)-2-Hydroxy-1-phenylethyl]amino-5,6,7,8-t...)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330225(CHEMBL1272004 | N-[(1R)-1-Phenylethyl]-N-(5,6,7,8-...)
Affinity DataIC50: >3.24E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) fibrillization (unknown origin) incubated with agitation for 1 min every hr measured over 80 hrs by thioflavin-T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330236((E)-1-(4-[(1S)-2-Hydroxy-1-phenylethyl]amino-5,6,7...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50467361(CHEMBL197478)
Affinity DataIC50:  4.20E+3nMAssay Description:Disaggregation of amyloid beta (1 to 42 residues) (unknown origin) preformed fibrils incubated with agitation for 1 min every hr measured over 80 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330244((E)-4-(Dimethylamino)-1-4-[(2-hydroxyethyl)amino]-...)
Affinity DataIC50:  4.88E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50467361(CHEMBL197478)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) fibrillization (unknown origin) incubated with agitation for 1 min every hr measured over 80 hrs by thioflavin-T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM4375((2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2...)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) fibrillization (unknown origin) incubated with agitation for 1 min every hr measured over 80 hrs by thioflavin-T...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330245(1-(4-[(1S)-2-Hydroxy-1-phenylethyl]amino-5,6,7,8-t...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EGFR at 20 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330226(2-(5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimi...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EGFR at 20 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330227((2R)-2-Phenyl-2-(5,6,7,8-tetrahydrobenzo[4,5]thien...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EGFR at 20 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330229((S)-2-Phenyl-2-(5,6,7,8-tetrahydro-pyrido[4',3':4,...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EGFR at 20 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50330246((E)-4-(Dimethylamino)-1-(4-[(1R)-2-hydroxy-1-pheny...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EGFR at 20 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed