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Found 7 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50322820'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50:  223nMAssay Description:Inhibition of GST-tagged human EGFR kinase domain (696 to 1022 residues) using poly(Glu, Tyr) 4:1 substrate incubated for 60 mins by kinase-Glo plus ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50:  223nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50:  223nMAssay Description:Inhibition of GST-tagged human EGFR kinase domain (696 to 1022 residues) using poly(Glu, Tyr) 4:1 substrate incubated for 60 mins by kinase-Glo plus ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50:  223nMAssay Description:Inhibition of GST-tagged EGFR expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50:  393nMAssay Description:Inhibition of human wild type GST-tagged EGFR kinase domain expressed in Sf9 cells by luminescence assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-tagged human EGFR kinase domain I858R/T790M mutant (696 to 1022 residues) using EGFR L858R/T790M substrate peptide incubated for 12...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50322820(CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-tagged human EGFR kinase domain I858R/T790M mutant (696 to 1022 residues) using EGFR L858R/T790M substrate peptide incubated for 12...More data for this Ligand-Target Pair