Compile Data Set for Download or QSAR
maximum 50k data
Found 57 with Last Name = 'claridge' and Initial = 'td'
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataIC50:  20nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303765(2-(3-hydroxy-2-((naphthalen-2-ylsulfonyl)carbonyli...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
TargetPeptidoglycan D,D-transpeptidase FtsI(Pseudomonas aeruginosa)
University of Oxford

LigandPNGBDBM50240426((2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazi...)
Affinity DataIC50:  166nMpH: 7.2 T: 2°CAssay Description:An appropriate amount of enzyme (4uM) was pre-incubated with the (5R)- or 5(S)-penicilloic acid in the assay buffer (50mM HEPES-NaOH buffer (pH 7.2) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50277935((S)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataIC50:  512nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519637(CHEMBL4550375)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of monoamino oxidase B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug and toxin extrusion protein 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519637(CHEMBL4550375)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of MATE1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50:  8.53E+4nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase FtsI(Pseudomonas aeruginosa)
University of Oxford

LigandPNGBDBM104100((5S)-PA | (5S)-Penicilloic acid)
Affinity DataIC50:  1.26E+5nMpH: 7.2 T: 2°CAssay Description:An appropriate amount of enzyme (4uM) was pre-incubated with the (5R)- or 5(S)-penicilloic acid in the assay buffer (50mM HEPES-NaOH buffer (pH 7.2) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase FtsI(Pseudomonas aeruginosa)
University of Oxford

LigandPNGBDBM104099((5R)-PA | (5R)-Penicilloic acid)
Affinity DataIC50:  1.96E+5nMpH: 7.2 T: 2°CAssay Description:An appropriate amount of enzyme (4uM) was pre-incubated with the (5R)- or 5(S)-penicilloic acid in the assay buffer (50mM HEPES-NaOH buffer (pH 7.2) ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26122((2E)-but-2-enedioic acid | FUMARIC ACID | Fumarate...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50277936((R)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303763((R)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303764((S)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50244093(1-hydroxypropane-1,2,3-tricarboxylate | isocitrate...)
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303766(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperature in presence of HIF1alpha (55...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 313K temperatureMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303766(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Affinity DataKd:  900nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303763((R)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataKd:  3.30E+4nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303764((S)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataKd:  3.50E+4nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50277936((R)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamid...)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(SUCCINIC ACID | Substrate analogue, 11 | Succinate...)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperatureMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 100% H2O MQC spectrometer operated at 23 MHz at 313K temperatureMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303766(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 313K temperatureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303766(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 100% H2O MQC spectrometer operated at 23 MHz at 313K temperatureMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataKd:  100nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26122((2E)-but-2-enedioic acid | FUMARIC ACID | Fumarate...)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(2,4 PDCA | cid_10365 | pyridine carboxylate, 6a | ...)
Affinity DataKd:  420nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataKd:  6.00E+4nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)ac...)
Affinity DataKd:  80nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataKd:  2.00E+3nMAssay Description:Displacement of [13C]-2OG from catalytic domain of PHD2 (181 to 426) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataKd:  110nMAssay Description:Displacement of [13C]-2OG from catalytic domain of PHD2 (181 to 426) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50303766(2-oxoglutaric acid | 2-oxopentanedioic acid | CHEM...)
Affinity DataKd:  900nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by 1H-15N HSQC titration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataEC50:  110nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519637(CHEMBL4550375)
Affinity DataEC50:  370nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519637(CHEMBL4550375)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519638(CHEMBL4442951)
Affinity DataEC50:  8.35E+3nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519636(BMN 195 | BMN-195 | Ezutromid | SMT-C1100 | SMTC-1...)
Affinity DataEC50:  1.28E+3nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUtrophin(Homo sapiens)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50519638(CHEMBL4442951)
Affinity DataEC50:  120nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 57 total ) | Next | Last >>
Jump to: