Affinity DataIC50: 20nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 166nMpH: 7.2 T: 2°CAssay Description:An appropriate amount of enzyme (4uM) was pre-incubated with the (5R)- or 5(S)-penicilloic acid in the assay buffer (50mM HEPES-NaOH buffer (pH 7.2) ...More data for this Ligand-Target Pair
Affinity DataIC50: 512nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of monoamino oxidase B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
TargetMultidrug and toxin extrusion protein 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MATE1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 8.53E+4nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+5nMpH: 7.2 T: 2°CAssay Description:An appropriate amount of enzyme (4uM) was pre-incubated with the (5R)- or 5(S)-penicilloic acid in the assay buffer (50mM HEPES-NaOH buffer (pH 7.2) ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+5nMpH: 7.2 T: 2°CAssay Description:An appropriate amount of enzyme (4uM) was pre-incubated with the (5R)- or 5(S)-penicilloic acid in the assay buffer (50mM HEPES-NaOH buffer (pH 7.2) ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperature in presence of HIF1alpha (55...More data for this Ligand-Target Pair
Affinity DataKd: 3.40E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 313K temperatureMore data for this Ligand-Target Pair
Affinity DataKd: 900nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
Affinity DataKd: 3.30E+4nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
Affinity DataKd: 3.50E+4nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
Affinity DataKd: 2.20E+4nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperatureMore data for this Ligand-Target Pair
Affinity DataKd: 2.80E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 100% H2O MQC spectrometer operated at 23 MHz at 313K temperatureMore data for this Ligand-Target Pair
Affinity DataKd: 2.20E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 313K temperatureMore data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMAssay Description:Binding affinity to human PHD2-Mn(II) using 100% H2O MQC spectrometer operated at 23 MHz at 313K temperatureMore data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+5nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataKd: 420nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataKd: 6.00E+4nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataKd: 80nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.00E+3nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Displacement of [13C]-2OG from catalytic domain of PHD2 (181 to 426) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Displacement of [13C]-2OG from catalytic domain of PHD2 (181 to 426) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKd: 900nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by 1H-15N HSQC titration assayMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
Affinity DataEC50: 370nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.35E+3nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
Affinity DataEC50: 1.28E+3nMAssay Description:Activation of human utrophin-1 in iDMD cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Activation of human utrophin-1 in mouse mdx myoblasts by H2K-mdx utrnA-luc assayMore data for this Ligand-Target Pair