Affinity DataIC50: 100nMAssay Description:Inhibition of bee venom group 3 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of pig pancreatic group 1 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno
Curated by ChEMBL
University Of Salerno
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-LO in A23187/AA-stimulated human intact neutrophils assessed as reduction in LTB4/5-HETE formation measured after 20 mins by RP-HPLC ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of mPGES-1 obtained from IL-beta stimulated human A549 cells microsomes assessed as residual activity by measuring conversion of PGH2 to P...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human synovial recombinant group 2 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.13E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.52E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of bee venom group 3 secretory phospholipase A2 by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.96E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.15E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)-mediated formation of uric acid by spectrophotometryMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 2.10E+4nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 1.80E+4nMAssay Description:Agonist activity at human full-length PXR transfected in human HepG2 cells co-transfected with pSG5-RXR assessed as induction of transactivation by d...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+4nMAssay Description:Transactivation of FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as beta-galactosidase activity after 18 hrs by luci...More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+4nMAssay Description:Antagonist activity at FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as inhibition of CDCA-induced transactivation a...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+4nMAssay Description:Antagonist activity at FXR (unknown origin) expressed in human HepG2 cells co-expressing RXR assessed as inhibition of CDCA-induced transactivation a...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Transactivation of human FXR transfected in human HepG2 cells by beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 2.20E+3nMAssay Description:Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 5.20E+3nMAssay Description:Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Transactivation of human GP-BAR1 transfected in HEK293T cells assessed as induction of intracellular cAMP production after 18 hrs by cAMP responsive ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Transactivation of GAL4-fused PPARgamma ligand binding domain transfected in human HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair