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Found 40 with Last Name = 'datta' and Initial = 's'
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50335519((S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-(...)
Affinity DataIC50:  41.4nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50484355(Skimmiarepin A)
Affinity DataIC50:  63nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50484356(Skimmiarepin C)
Affinity DataIC50:  68nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485671(ADOCIAQUINONE A | Adociaquinones A)
Affinity DataIC50:  200nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  200nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485669((+)-14-Hydroxymethylxestoquinone | CHEMBL2153503)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485670((+)-15-Hydroxymethylxestoquinone | CHEMBL2153504)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485669((+)-14-Hydroxymethylxestoquinone | CHEMBL2153503)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50103513(CHEBI:17076 | Chemform | Gerox | NSC-14083 | Strep...)
Affinity DataIC50:  2.23E+3nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485670((+)-15-Hydroxymethylxestoquinone | CHEMBL2153504)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485673((+)-14,15-Dihydroxestoquinone | CHEMBL2153505)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50484356(Skimmiarepin C)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of 1, 10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485671(ADOCIAQUINONE A | Adociaquinones A)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50484355(Skimmiarepin A)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 1, 10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485673((+)-14,15-Dihydroxestoquinone | CHEMBL2153505)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50398330(XESTOQUINONE)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of GST-tagged p53 binding to Hdm2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50221769(CHEMBL166184)
Affinity DataIC50:  1.70E+4nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50221777(CHEMBL352932)
Affinity DataIC50:  2.55E+4nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485672(Xestoquinol Sulfate)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50485672(Xestoquinol Sulfate)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by HRE3-TK-luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50221774(CHEMBL353406)
Affinity DataIC50:  7.17E+4nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50221746(CHEMBL354064)
Affinity DataIC50:  9.95E+4nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50221744(CHEMBL349656)
Affinity DataIC50:  1.07E+5nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50221745(CHEMBL350726)
Affinity DataIC50:  1.10E+5nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327208(CHEMBL1256053 | tert-butyl (S)-1-((S)-1-((S)-3-(1H...)
Affinity DataIC50:  1.92E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327213((3S,6S,9S,12S,15S,18S)-3-benzyl-6-sec-butyl-15,18-...)
Affinity DataIC50:  2.09E+5nMAssay Description:Inhibition of GST-tagged p53 binding to Hdm2 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327210(CHEMBL1256067 | isobutyl (6S,9S,12S)-9-((1H-indol-...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327209((4S,7S,10S)-7-((1H-indol-3-yl)methyl)-15-amino-4-b...)
Affinity DataIC50:  3.07E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327211(CHEMBL1256064 | tert-butyl (6S,9S,12S)-9-((1H-indo...)
Affinity DataIC50:  3.39E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327212(CHEMBL1256044 | benzyl (6S,9S,12S)-9-((1H-indol-3-...)
Affinity DataIC50:  3.48E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50221743(CHEMBL352152)
Affinity DataIC50: >4.14E+5nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Rattus norvegicus)
National Chemical Laboratory (Csir-Ncl)

Curated by ChEMBL
LigandPNGBDBM50221775(CHEMBL164621)
Affinity DataIC50: >4.61E+5nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327207(((S)-5-((S)-3-(1H-indol-3-yl)-1-oxo-1-((S)-1-oxo-3...)
Affinity DataIC50:  4.63E+5nMAssay Description:Inhibition of GST-tagged p53 binding to MDMX by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataKd:  75nMAssay Description:Binding affinity to Hdm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataKd:  75nMAssay Description:Binding affinity to Hdm2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein Mdm4(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50327206((2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-ind...)
Affinity DataKd:  390nMAssay Description:Binding affinity to MDMXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed