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Found 174 with Last Name = 'elowe' and Initial = 'n'
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370860(CHEMBL219268)
Affinity DataIC50:  79nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294576((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370870(CHEMBL218090)
Affinity DataIC50:  280nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294482(CHEMBL552309 | S-tubercidinylhomocysteine)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294557((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370869(CHEMBL220764)
Affinity DataIC50:  530nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DNMT3b2 at 45 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294494(2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-ph...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370861(CHEMBL221848)
Affinity DataIC50:  650nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294574((2S,4S)-4-(((2S,3S,4R,5S)-5-(6-amino-2-chloro-9H-p...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294497(4-(((2S,3S,4R,5R)-5-(6-(3,5-dimethoxybenzylamino)-...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294577((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  920nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294492(2-amino-4-(((2S,3S,4R,5R)-5-(6-(benzylamino)-9H-pu...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294488(2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-methyl-9H-p...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294557((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294559((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294482(CHEMBL552309 | S-tubercidinylhomocysteine)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370865(CHEMBL221706)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294574((2S,4S)-4-(((2S,3S,4R,5S)-5-(6-amino-2-chloro-9H-p...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294493(2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(phen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294491(2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(phen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370853(CHEMBL221182)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294485(2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-fluoro-9H-p...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294577((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370850(CHEMBL373750)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294486(2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-chloro-9H-p...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294483(2-amino-4-(((2S,3S,4R,5R)-5-(7-amino-3H-[1,2,3]tri...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370867(CHEMBL221705)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294496(2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(pyri...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294576((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294562((2S,4S)-methyl 4-(((2S,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370855(CHEMBL218737)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294564((2S,4S)-methyl 4-(((2S,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294565((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((R)-py...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294556((2S,3R,4S,5S)-2-(6-(2-(biphenyl-4-yl)ethylamino)-2...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294495((2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370857(CHEMBL220531)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294488(2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-methyl-9H-p...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370854(CHEMBL220494)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294498(2-Amino-4-{(2S,3S,4R,5R)-5-[6-(2-biphenyl-4-yl-eth...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294481(2-amino-4-(((2S,3S,4R,5R)-5-(4-amino-1H-imidazo[4,...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294485(2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-fluoro-9H-p...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human recombinant DNMT3b2 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystathionine beta-lyase MetC(Escherichia coli K-12)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50370864(CHEMBL451558)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of Escherichia coli CBLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294494(2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-ph...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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