TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.0210nM ΔG°: -63.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.0400nM ΔG°: -61.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,I543V,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.190nM ΔG°: -57.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,M535I,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.5nM ΔG°: -55.2kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,L552P,A560V,V571A,I573V,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.550nMAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 0.700nM ΔG°: -54.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 1.20nM ΔG°: -53.0kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,M535I,L552P,A560V,V571A,I573V,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 2.20nMAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 3.10nM ΔG°: -50.5kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,M535I,I543V,L552P,A560V,V571A,I573V,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 5.60nMAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]-WIN-35,428 from Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:In vitro inhibition of [3H]-NE re-uptake into synaptosomeMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,I543V,L552P,A560V,V571A,I573V,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 9.40nMAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 17nM ΔG°: -46.1kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity against HRV-14 3C protease.More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]-WIN-35,428 from Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,I543V,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 23nM ΔG°: -45.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,L552P,A560V,V571A,I573V,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 24nMAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:In vitro inhibition of DA re-uptake into synaptosomeMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:In vitro ability of compound to inhibit 5-HT re-uptake of radiolabelled [3H]-tritium trasmitter into synaptosomeMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-WIN-35,428 from Dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Inhibition of human rhinovirus 3C proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Catalytic rate constant (Kobs/[I]) of the compound was evaluated against human rhinovirus (HRV) serotype 14 3C Protease (3CP)More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587,K509R,V521I,L522F,M525I,L552P,A560V,V571A,L579M](Human immunodeficiency virus type 1)
University of Florida College of Medicine
University of Florida College of Medicine
Affinity DataKi: 30nM ΔG°: -44.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair