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Found 155 with Last Name = 'fukuda' and Initial = 'jy'
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4817(N-[2-(dimethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo...)
Affinity DataIC50:  0.5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4818(5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yli...)
Affinity DataIC50:  1nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4821(5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yli...)
Affinity DataIC50:  1nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437671(CHEMBL2408057)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437674(CHEMBL2408066)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437660(CHEMBL2408058)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437663(CHEMBL2408059)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4820(5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yli...)
Affinity DataIC50:  2nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataIC50:  2nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437669(CHEMBL2408056)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437666(CHEMBL2408055)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437662(CHEMBL2408061)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4819(5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yli...)
Affinity DataIC50:  3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437674(CHEMBL2408066)
Affinity DataIC50:  3nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4815(5-{[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-yli...)
Affinity DataIC50:  3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437668(CHEMBL2407099)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437665(CHEMBL2408065)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437673(CHEMBL2407892)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437675(CHEMBL2408062)
Affinity DataIC50:  4nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437672(CHEMBL2408060)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4816(5-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylid...)
Affinity DataIC50:  5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437664(CHEMBL2408063)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437667(CHEMBL2408064)
Affinity DataIC50:  6nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437657(CHEMBL2408067)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437661(CHEMBL2407882)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4822(5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yli...)
Affinity DataIC50:  10nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437656(CHEMBL2407888)
Affinity DataIC50:  10nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50433575(CHEMBL2381700)
Affinity DataIC50:  11nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437652(CHEMBL2408069)
Affinity DataIC50:  12nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437662(CHEMBL2408061)
Affinity DataIC50:  12nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437665(CHEMBL2408065)
Affinity DataIC50:  12nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437664(CHEMBL2408063)
Affinity DataIC50:  14nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437649(CHEMBL2408070)
Affinity DataIC50:  16nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

LigandPNGBDBM4813(N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...)
Affinity DataIC50:  17nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437651(CHEMBL2408068)
Affinity DataIC50:  19nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437646(CHEMBL2407881)
Affinity DataIC50:  23nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437650(CHEMBL2407883)
Affinity DataIC50:  23nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437653(CHEMBL2407891)
Affinity DataIC50:  23nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4819(5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yli...)
Affinity DataIC50:  25nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437644(CHEMBL2407880)
Affinity DataIC50:  27nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4815(5-{[(3Z)-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-yli...)
Affinity DataIC50:  27nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437660(CHEMBL2408058)
Affinity DataIC50:  29nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437652(CHEMBL2408069)
Affinity DataIC50:  29nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437673(CHEMBL2407892)
Affinity DataIC50:  30nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437668(CHEMBL2407099)
Affinity DataIC50:  31nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sugen

LigandPNGBDBM4816(5-{[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylid...)
Affinity DataIC50:  32nMpH: 7.5 T: 2°CAssay Description:The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437663(CHEMBL2408059)
Affinity DataIC50:  36nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437640(CHEMBL1684983)
Affinity DataIC50:  37nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437659(CHEMBL2407889)
Affinity DataIC50:  38nMAssay Description:Inhibition of alpha4beta1 integrin-mediated human jurkat cell adhesion to fibronectin in absence of human serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-7(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437671(CHEMBL2408057)
Affinity DataIC50:  50nMAssay Description:Inhibition of alpha4beta7 integrin-mediated human 8866 cell adhesion to MadCAM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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