Found 26 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM4814' TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity to PDGFR-beta (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of PDGFRbeta (unknown origin) phosphorylationMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human PDGFRbeta after 30 mins by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of PDGFRbeta (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of PDGFR-beta (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of PDGFRbeta autophosphorylation by cell based western blot analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PDGFR-beta in human U251 cells compound pretreated for 60 min before PDGF-BB stimulation for 10 mins by phosphotyrosine ELISA cytoblot ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PDGFRbeta in human SH-SY5Y cells preincubated for 60 mins followed by PDGF stimulation and measured after 10 mins by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PDGFR-beta in human SF539 cells assessed as reduction in PDGF-BB induced phosphorylation preincubated for 60 mins followed by PDGF-BB a...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PDGFRbeta in human SH-SY5Y cells by phosphotyrosine ELISA assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PDGF-BB-induced PDGFRbeta activation in human SH-SY5Y cells pretreated for 60 mins followed by PDGF-BB addition and measured after 10 m...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of PDGFRbeta phosphorylation in human SF539 cells after 10 mins by FLISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of PDGFRbeta tyrosine kinase activity in PDGF-BB-stimulated human SF-539 cells after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of PDGFRbeta expressed in human A431 cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 8.31E+4nMAssay Description:Inhibition of PDGF-BB-induced PDGFR beta phosphorylation in human SF539 cells overexpressing PDGFR beta pretreated for 60 mins prior to PDGF-BB addit...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 8.31E+4nMAssay Description:Inhibition of PDGFRbeta in human SF539 cells assessed as inhibition of PDGFR-BB-induced tyrosine phosphorylation incubated for 60 mins prior to EGF-a...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 8.31E+4nMAssay Description:Inhibition of PDGFRbeta in human SF539 cells pretreated for 60 mins measured after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataKd: 0.210nMAssay Description:Average Binding Constant for PDGFRB; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataKd: 0.200nMAssay Description:Inhibition of PDGFRbeta by cellular assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataKd: 0.0750nMAssay Description:Binding affinity to PDGFRBMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataKd: 0.0800nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataKd: 0.0750nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Qilu Pharmaceutical
Curated by ChEMBL
Qilu Pharmaceutical
Curated by ChEMBL
Affinity DataKd: 0.0750nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
