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Found 26 with Last Name = 'gainsford' and Initial = 'gj'
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  0.0110nMAssay Description:Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50122726(2-Hydroxymethyl-5-(4-hydroxy-5H-pyrrolo[3,2-d]pyri...)
Affinity DataKi:  0.0230nMAssay Description:Inhibitory activity of compound against bovine purine nucleoside phosphorylase(PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50293086((1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-...)
Affinity DataKi:  0.0290nMAssay Description:Inhibitory activity of compound against human purine nucleoside phosphorylase(PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50293086((1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-...)
Affinity DataKi:  0.0300nMAssay Description:Inhibitory activity of compound against bovine purine nucleoside phosphorylase(PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50422435(CHEMBL2311112)
Affinity DataKi:  0.0420nMAssay Description:Inhibitory activity of compound against bovine purine nucleoside phosphorylase(PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bos taurus (bovine))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50122724(4-Amino-5-(3,4-dihydroxy-5-hydroxymethyl-pyrrolidi...)
Affinity DataKi:  0.0600nMAssay Description:Inhibitory activity of compound against bovine purine nucleoside phosphorylase(PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  0.0660nMAssay Description:Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  0.0660nMAssay Description:Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50122726(2-Hydroxymethyl-5-(4-hydroxy-5H-pyrrolo[3,2-d]pyri...)
Affinity DataKi:  0.0720nMAssay Description:Inhibitory activity of compound against human purine nucleoside phosphorylase(PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50122724(4-Amino-5-(3,4-dihydroxy-5-hydroxymethyl-pyrrolidi...)
Affinity DataKi:  0.0960nMAssay Description:Inhibitory activity of compound against human purine nucleoside phosphorylase(PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50422435(CHEMBL2311112)
Affinity DataKi:  0.104nMAssay Description:Inhibitory activity of compound against human purine nucleoside phosphorylase(PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM22109(7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252909((3R,4R)-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fluo...)
Affinity DataKi:  1.82nMAssay Description:Inhibition of human purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252909((3R,4R)-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fluo...)
Affinity DataKi:  18nMAssay Description:Inhibition of human purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  23.3nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252865((+/-)-cis-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fl...)
Affinity DataKi:  23.3nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  80nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252909((3R,4R)-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fluo...)
Affinity DataKi:  260nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50247158(7-(((3S,4S)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Industrial Research

Curated by ChEMBL
LigandPNGBDBM50252909((3R,4R)-1-((9-Deazahypoxanthin-9-yl)methyl)-4-fluo...)
Affinity DataKi:  2.07E+3nMAssay Description:Inhibition of Plasmodium falciparum purine nucleoside phosphorylase assessed as slow onset inhibition constant by xanthine-oxidase coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed