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Found 608 with Last Name = 'garst' and Initial = 'me'
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285708(US10077289, Compound 16 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  0.720nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052882(AGN-193080 | CHEMBL298936 | Imidazolidin-2-ylidene...)
Affinity DataKi:  1.20nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285706(US10077289, Compound 14 | [(2S,3R,4R)-7-(5-Fluoro-...)
Affinity DataKi:  1.5nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataKi:  1.5nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50055832((1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4...)
Affinity DataKi:  1.70nMAssay Description:Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052880(CHEMBL49137 | Imidazolidin-2-ylidene-(5-methyl-qui...)
Affinity DataKi:  2nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052880(CHEMBL49137 | Imidazolidin-2-ylidene-(5-methyl-qui...)
Affinity DataKi:  2nMAssay Description:Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285715(US10077289, Compound 23 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  2.10nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285710(US10077289, Compound 18 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  2.20nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285701(US10077289, Compound 9 | [(2S,3R,4R)-1-(1H-Benzimi...)
Affinity DataKi:  2.30nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285707(US10077289, Compound 15 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  2.5nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM34572(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)
Affinity DataKi:  2.70nMAssay Description:Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50021812(2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-...)
Affinity DataKi:  2.90nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285725(US10077289, Compound 33 | [2S,3R,4R)-3-Hydroxy-4-m...)
Affinity DataKi:  3.10nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285726(US10077289, Compound 34 | [2S,3R,4R)-3-Hydroxy-4-m...)
Affinity DataKi:  3.10nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285705(US10077289, Compound 13 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  3.20nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285714(US10077289, Compound 22 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  3.20nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285713(US10077289, Compound 21 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  3.20nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285716(US10077289, Compound 24 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  3.5nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285704(US10077289, Compound 12 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  3.80nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity for human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285717(US10077289, Compound 25 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  3.80nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
Affinity DataKi:  3.80nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285720(US10077289, Compound 28 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  3.90nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285709(US10077289, Compound 17 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  3.90nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285697(US10077289, Compound 5 | [(2S,3R,4R)-3-Hydroxy-4-m...)
Affinity DataKi:  4.10nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285727(US10077289, Compound 35 | [2S,3R,4R)-3-Hydroxy-4-m...)
Affinity DataKi:  4.40nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285693(US10077289, Compound 2 | [(2S,3R,4R)-3-Hydroxy-4-m...)
Affinity DataKi:  4.60nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Allergan

Curated by ChEMBL
LigandPNGBDBM50021812(2,6-Dichloro-N-imidazolidin-2-ylidene-benzene-1,4-...)
Affinity DataKi:  4.80nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2B adrenergic receptor from cloned rat RNG receptor transfected into Chinese hamster ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50055835((4-tert-Butyl-3-methoxy-2,6-dimethyl-phenyl)-(1H-i...)
Affinity DataKi:  4.90nMAssay Description:Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285698(US10077289, Compound 6 | [(2S,3R,4R)-3-Hydroxy-5-(...)
Affinity DataKi:  5.10nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285695(US10077289, Compound 4 | [(2S,3R,4R)-5-(1-(N,N-Dim...)
Affinity DataKi:  5.10nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285711(US10077289, Compound 19 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  5.40nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285703(US10077289, Compound 11 | [(2S,3R,4S)-3-Hydroxy-4-...)
Affinity DataKi:  5.60nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285729(US10077289, Compound 37 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  5.60nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285699(US10077289, Compound 7 | [(2S,3R,4R)-3-Hydroxy-4-m...)
Affinity DataKi:  5.60nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285712(US10077289, Compound 20 | [(2S,3R,4R)-3-Hydroxy-7-...)
Affinity DataKi:  5.70nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50055830((1H-Imidazol-2-yl)-(5-methyl-3,4-dihydro-2H-benzo[...)
Affinity DataKi:  6nMAssay Description:Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285719(US10077289, Compound 27 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  6.80nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285702(US10077289, Compound 10 | [(2S,3R,4R)-1-(1H-Benzim...)
Affinity DataKi:  7.10nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285700(US10077289, Compound 8 | [(2S,3R,4R)-3-Hydroxy-4-m...)
Affinity DataKi:  7.40nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285728(US10077289, Compound 36 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  7.70nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285724(US10077289, Compound 32 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  8.30nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Allergan

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity for rat Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(NEONATAL RAT)
Allergan

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
Affinity DataKi:  8.30nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2B adrenergic receptor from cloned rat RNG receptor transfected into Chinese hamster ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285694(US10077289, Compound 3 | [(2S,3R,4R)-3-Hydroxy-4-m...)
Affinity DataKi:  8.60nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNischarin(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50016897(2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...)
Affinity DataKi:  8.90nMAssay Description:Displacement of [3H]-clonidine from bovine imidazoline receptor I-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052882(AGN-193080 | CHEMBL298936 | Imidazolidin-2-ylidene...)
Affinity DataKi:  8.90nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2C adrenergic receptor from cloned human C-2 receptor transfected into Chinese hamste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM285723(US10077289, Compound 31 | [(2S,3R,4R)-3-Hydroxy-4-...)
Affinity DataKi:  9.5nMpH: 7.8Assay Description:The protease-free PPIase assay measures the rate of cis to trans conversion of a peptide substrate catalyzed by the enzyme cyclophilin A. Addition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50052881(AGN-192172 | CHEMBL49284 | Imidazolidin-2-ylidene-...)
Affinity DataKi:  9.60nMAssay Description:Compound was tested in vitro for binding affinity against Alpha-2A adrenergic receptor from cloned human C-10 receptor transfected into Chinese hamst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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