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Found 20 with Last Name = 'grabley' and Initial = 's'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of human FK506 binding protein 12 (Conc=14 nM) of FKBPsfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP4(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  2.42E+4nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of rabbit FK506 binding protein 52 (Conc=52 nM) of FKBPsfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP14(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  7.62E+4nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of Photobacterium sp. FK506 binding protein 22 (Conc=41 nM) of FKBPsfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP3(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  1.24E+5nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of L. pneumophilia FK506 binding protein 25 (Conc=40 nM) of FKBPsfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 4(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi:  1.87E+5nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of E. coli parvulin (Conc=4 nM) of Parvulins sfamilyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition constant(Ki) for inhibition of PPIase activity of human Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Conc=4 nM) of Parvulins fa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080528(3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)...)
Affinity DataIC50:  3.60E+3nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080534(CHEMBL333448 | ethyl (4-{(2R)-2-[(1S,3S,5S)-3,5-di...)
Affinity DataIC50:  4.40E+3nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Leibniz-Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human recombinant DYRK1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080531(2-{4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohe...)
Affinity DataIC50:  2.16E+4nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080530(4-{4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohe...)
Affinity DataIC50:  2.23E+4nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080532(4-{4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohe...)
Affinity DataIC50:  6.82E+4nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Leibniz-Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM50326169((S)-methyl 4-hydroxy-2-(4-hydroxy-3-(3-methylbut-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DYRK1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Leibniz-Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM50242741(CHEMBL460464 | butyrolactone I 3-sulfate)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DYRK1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Leibniz-Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM50251336(CHEMBL465047 | butyrolactone I 4''-sulfate)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant DYRK1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080535(1-Benzyl-4-[(R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxo-c...)
Affinity DataIC50:  1.17E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080527(4-[(R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxo-cyclohexyl...)
Affinity DataIC50:  1.24E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080536(4-((R)-2-Hydroxy-2-{(1R,3S,5S)-2-[(Z)-hydroxyimino...)
Affinity DataIC50:  1.77E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080533(CHEMBL331865 | {4-[(R)-2-(Adamantan-1-ylcarbamoylo...)
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Max-Planck Research Unit

Curated by ChEMBL
LigandPNGBDBM50080529(Acetic acid (R)-1-((1S,3S,5S)-3,5-dimethyl-2-oxo-c...)
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was evaluated for its inhibitory effect on human FK506 binding protein 12 by means of protease-coupled PPIase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed