Compile Data Set for Download or QSAR
maximum 50k data
Found 11 with Last Name = 'grum-tokars' and Initial = 'v'
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM13925((3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl ...)
Affinity DataKi:  0.00450nM ΔG°:  -64.8kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)
Affinity DataKi:  0.0140nM ΔG°:  -62.0kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM13924((3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl ...)
Affinity DataKi:  0.140nM ΔG°:  -56.2kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM13926((2R,3aR,6aS)-octahydropentalen-2-yl N-[(2S,3R)-3-h...)
Affinity DataKi:  5.30nM ΔG°:  -47.2kJ/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined by substrate cleavage assay using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-Arg-NH2. A standar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477129(CHEMBL397154 | acs.jmedchem.1c00409_ST.512)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477130(CHEMBL235873 | acs.jmedchem.1c00409_ST.563)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477128(CHEMBL238217 | GRL-0155S)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477127(CHEMBL393608)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM11249(AG7088 analogue 2c | ethyl (2E,4S)-4-[(2S)-2-[(2S)...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50176014((S,E)-ethyl 4-((2R,5S)-6-methyl-2-(3-methylbut-2-e...)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Purdue University

Curated by ChEMBL
LigandPNGBDBM11245(AG7088 analogue 1c | CHEMBL194398 | ethyl (2E,4S)-...)
Affinity DataIC50:  8.70E+5nMAssay Description:Inhibition of SARS-CoV 3C-like protease by FRET based microplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed