Affinity DataKi: 0.100nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Inhibitory activity against 5HT5A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 1.18nMAssay Description:Inhibitory activity against dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibitory activity against 5HT2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibitory activity against dopamine D2(long) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibitory activity against dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 1.46nMAssay Description:Inhibitory activity against dopamine D2(long) receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Qbi Covid-19 Research Group (Qcrg)
Curated by ChEMBL
Qbi Covid-19 Research Group (Qcrg)
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Qbi Covid-19 Research Group (Qcrg)
Curated by ChEMBL
Qbi Covid-19 Research Group (Qcrg)
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-pentazocin from the Sigma1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Qbi Covid-19 Research Group (Qcrg)
Curated by ChEMBL
Qbi Covid-19 Research Group (Qcrg)
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-DTG from the Sigma2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.48nMAssay Description:Inhibitory activity against 5HT7 receptorMore data for this Ligand-Target Pair