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Found 32 with Last Name = 'henwood' and Initial = 'a'
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386376(CHEMBL2046865)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123474(1-[9-(3-Chloro-4-methoxy-benzylamino)-3-ethyl-3H-2...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123477(CHEMBL344018 | N*9*-(3-Chloro-4-methoxy-benzyl)-3-...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123473(1-[9-(3-Chloro-4-methoxy-benzylamino)-3-ethyl-3H-2...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50089814(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-pi...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50089814(4-(3-Chloro-4-methoxy-benzylamino)-1-(4-hydroxy-pi...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14776(2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phen...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50123475(1-[9-(3-Chloro-4-methoxy-benzylamino)-3-ethyl-3H-2...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098220(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098220(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098226(4-(1-Cyclohexyl-ethylamino)-1-ethyl-1H-pyrazolo[3,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098225(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098219(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098222(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098223(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50:  38nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386365(CHEMBL2046867)
Affinity DataIC50:  62nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386375(CHEMBL2046864)
Affinity DataIC50:  120nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386372(CHEMBL2046861)
Affinity DataIC50:  170nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098221(4-Butylamino-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386374(CHEMBL2046863)
Affinity DataIC50:  180nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386369(CHEMBL2046858)
Affinity DataIC50:  190nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386368(CHEMBL2046870)
Affinity DataIC50:  300nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386371(CHEMBL2046860)
Affinity DataIC50:  460nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386373(CHEMBL2046862)
Affinity DataIC50:  550nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386367(CHEMBL2046869)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386366(CHEMBL2046868)
Affinity DataIC50:  2.20E+3nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50386370(CHEMBL2046859)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]peptideYY from NPY1 receptor in human SK-N-MC cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098220(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataEC50:  44nMAssay Description:Relaxant effect on rabbit corpus cavernosal tissue stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataEC50:  42nMAssay Description:Relaxant effect on rabbit corpus cavernosal tissue stripsMore data for this Ligand-Target Pair