BDBM50098220 4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (pyridin-4-ylmethyl)-amide::4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-4,5-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (pyridin-4-ylmethyl)-amide::CHEMBL7868

SMILES CCn1ncc2c(NCc3ccc(OC)c(Cl)c3)c(cnc12)C(=O)NCc1ccncc1

InChI Key InChIKey=NJAQIMZSDVLFQH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098220   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098220(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of Phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098220(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098220(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataEC50:  44nMAssay Description:Relaxant effect on rabbit corpus cavernosal tissue stripsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed