Affinity DataKi: 3.60nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 6.80nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
TargetBifunctional glutamate/proline--tRNA ligase(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 31nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 86nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 134nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 437nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Compound tested for the inhibition of E. coli Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against human phenylalanyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: <2nMAssay Description:Compound tested for the inhibition of E. coli Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:In vitro displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureusMore data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha subunit(Streptococcus pyogenes serotype M18)
Cubist Pharmaceuticals
Curated by ChEMBL
Cubist Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalisMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair