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Found 28 with Last Name = 'hull' and Initial = 'we'
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.95nMAssay Description:Binding affinity was measured on Sigma receptor type 1 with guinea pig membranes and [3H]- pentazocine as ligand.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  46.5nMAssay Description:Binding affinity was measured on Sigma receptor type 2 with rat liver membranes and [3H]- DTG as ligand.More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092739(CHEMBL126131 | N-(2-Diethylamino-ethyl)-5-iodo-2-m...)
Affinity DataKi:  92nMAssay Description:Binding affinity was measured on Sigma receptor type 1 with guinea pig membranes and [3H]- pentazocine as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092741(CHEMBL338468 | N-(2-Diethylamino-ethyl)-3-iodo-4-m...)
Affinity DataKi:  249nMAssay Description:Binding affinity was measured on Sigma receptor type 1 with guinea pig membranes and [3H]- pentazocine as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092738(4-Amino-5-bromo-N-(2-diethylamino-ethyl)-3-iodo-2-...)
Affinity DataKi:  278nMAssay Description:Binding affinity was measured on Sigma receptor type 1 with guinea pig membranes and [3H]- pentazocine as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092737(CHEMBL339009 | N-(2-Diethylamino-ethyl)-2-iodo-5-m...)
Affinity DataKi:  347nMAssay Description:Binding affinity was measured on Sigma receptor type 2 with rat liver membranes and [3H]- DTG as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092737(CHEMBL339009 | N-(2-Diethylamino-ethyl)-2-iodo-5-m...)
Affinity DataKi:  455nMAssay Description:Binding affinity was measured on Sigma receptor type 1 with guinea pig membranes and [3H]- pentazocine as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092736(4-Amino-N-(2-diethylamino-ethyl)-5-iodo-2-methoxy-...)
Affinity DataKi:  484nMAssay Description:Binding affinity was measured on Sigma receptor type 1 with guinea pig membranes and [3H]- pentazocine as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092739(CHEMBL126131 | N-(2-Diethylamino-ethyl)-5-iodo-2-m...)
Affinity DataKi:  1.02E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 with rat liver membranes and [3H]- DTG as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092738(4-Amino-5-bromo-N-(2-diethylamino-ethyl)-3-iodo-2-...)
Affinity DataKi:  2.35E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 with rat liver membranes and [3H]- DTG as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092742(4-Acetylamino-N-(2-diethylamino-ethyl)-3-iodo-benz...)
Affinity DataKi:  4.65E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 1 with guinea pig membranes and [3H]- pentazocine as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092740(4-Acetylamino-N-(2-diethylamino-ethyl)-5-iodo-2-me...)
Affinity DataKi:  5.19E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 1 with guinea pig membranes and [3H]- pentazocine as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092741(CHEMBL338468 | N-(2-Diethylamino-ethyl)-3-iodo-4-m...)
Affinity DataKi:  6.52E+3nMAssay Description:Binding affinity was measured on Sigma receptor type 2 with rat liver membranes and [3H]- DTG as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092736(4-Amino-N-(2-diethylamino-ethyl)-5-iodo-2-methoxy-...)
Affinity DataKi:  2.14E+4nMAssay Description:Binding affinity was measured on Sigma receptor type 2 with rat liver membranes and [3H]- DTG as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092740(4-Acetylamino-N-(2-diethylamino-ethyl)-5-iodo-2-me...)
Affinity DataKi:  1.15E+5nMAssay Description:Binding affinity was measured on Sigma receptor type 2 with rat liver membranes and [3H]- DTG as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Heidelberg

Curated by ChEMBL
LigandPNGBDBM50092742(4-Acetylamino-N-(2-diethylamino-ethyl)-3-iodo-benz...)
Affinity DataKi:  1.48E+5nMAssay Description:Binding affinity was measured on Sigma receptor type 2 with rat liver membranes and [3H]- DTG as ligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106517(6-(4-Bromo-thiophen-2-ylmethoxy)-9H-purin-2-ylamin...)
Affinity DataIC50:  9nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106518(2-{10-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pu...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106510(2-{12-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pu...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106511(2-{8-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106515(7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106514(2-{4-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106513(2-{4-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106512(2-{6-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM5491(6-(benzyloxy)-9H-purin-2-amine | CHEMBL407874 | O6...)
Affinity DataIC50:  620nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106509(2-{2-[2-Amino-6-(4-bromo-thiophen-2-ylmethoxy)-pur...)
Affinity DataIC50:  680nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106519(2-[2-(5-Amino-7-benzyloxy-[1,2,3]triazolo[4,5-d]py...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
German Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50106516(2-[2-(2-Amino-6-benzyloxy-purin-9-yl)-ethoxy]-6-hy...)
Affinity DataIC50:  2.50E+4nMAssay Description:In vitro inhibition of MGMT using cell free extracts from HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed