TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 327nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 364nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 787nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 798nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 862nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 947nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 984nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.95E+3nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.99E+3nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.71E+3nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 5.70E+3nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 6.53E+3nMAssay Description:Displacement of labelled MK-499 from cloned channel hERG expressed in HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.20E+4nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.50E+4nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.00E+4nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for Potassium channel HERG Kv11.1More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.330nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.340nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.480nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.620nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Displacement of [125I]-labelled substance P from the cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair