Found 159 with Last Name = 'kondo' and Initial = 'n' TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University
Curated by ChEMBL
Kobe Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University
Curated by ChEMBL
Kobe Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University
Curated by ChEMBL
Kobe Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
3D Structure (crystal)TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of ACSL1 (unknown origin) assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by ...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University
Curated by ChEMBL
Kobe Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 297nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of ACSL1 (unknown origin) assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by ...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) cells using S-ad...More data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of NNMT in HEK293 cells measured after 20 to 24 hrs by RapidFire Mass SpectrometryMore data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Homo sapiens)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
Affinity DataIC50: 403nMAssay Description:Inhibition of recombinant human MMP13 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
TargetLong-chain-fatty-acid--CoA ligase 1(Mus musculus)
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Shionogi Pharmaceutical Research Center
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant mouse ACSL1 assessed as reduction in acetyl-coA prodution incubated for 90 mins in presence of Coenzyme A, ATP and MgCl2 by...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Kobe Pharmaceutical University
Curated by ChEMBL
Kobe Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 502nMAssay Description:Inhibition of recombinant human MMP12 using Mca-Pro-Leu-Gly-Leu-Dpa(Dnp)-Ala-Arg-NH2 as substrate after 30 mins by fluorescence spectrometryMore data for this Ligand-Target Pair
