TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0620nMAssay Description:Dissociation constant obtained by inhibition of Wild-type proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.0620nMAssay Description:Dissociation constant obtained by inhibition of Wild-type proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Dissociation constant obtained by inhibition of Wild-type proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Dissociation constant obtained by inhibition of Wild-type proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (K-60)More data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (A-44)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (A-44)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (A-44)More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DataKi: 19nM ΔG°: -43.6kJ/mole IC50: 4nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (V-18)More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibitory activity of the compound against thrombin (IIa) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (V-18)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (K-60)More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DataKi: 36nM ΔG°: -42.1kJ/mole IC50: 17nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (K-60)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (V-18)More data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Binding affinity towards thrombin was evaluatedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (K-60)More data for this Ligand-Target Pair
Affinity DataKi: 59nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (A-44)More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Binding affinity towards thrombin was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 100nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Affinity DataKi: 100nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 117nMAssay Description:Dissociation constant obtained by inhibition of mutant HIV-protease (V-18)More data for this Ligand-Target Pair
Affinity DataKi: 138nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Affinity DataKi: 156nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
TargetProtein kinase C alpha/beta/gamma/delta/epsilon/eta/theta type/Serine/threonine-protein kinase D1/D3(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Displacement of [3H]PDBu binding to Protein kinase C of CEM cells with 10% fetal calf serumMore data for this Ligand-Target Pair
Affinity DataKi: 204nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair