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Found 643 with Last Name = 'luciani' and Initial = 'r'
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  0.000340nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50022238((R)-5-Fluoro-1-((4S,5R)-4-hydroxy-5-methylphosphat...)
Affinity DataKi:  14nMAssay Description:Inhibition of human thymidylate synthase expressed in Escherichia coli incubated for 1 hr by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50123588(CHEMBL297258)
Affinity DataKi:  29nMAssay Description:Competitive inhibition of human FolD dehydrogenase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398391(CHEMBL2178602)
Affinity DataKi:  30nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398394(CHEMBL1232702)
Affinity DataKi:  37nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398392(CHEMBL2178603)
Affinity DataKi:  60nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398390(CHEMBL2177120)
Affinity DataKi:  78nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398395(CHEMBL1232399)
Affinity DataKi:  100nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398389(CHEMBL2178601)
Affinity DataKi:  100nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  180nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448368(CHEMBL3121472)
Affinity DataKi:  200nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398396(CHEMBL2178600)
Affinity DataKi:  210nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448344(CHEMBL3121462)
Affinity DataKi:  270nMAssay Description:Competitive inhibition of human thymidylate synthase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50443313(CHEMBL3088233)
Affinity DataKi:  310nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPteridine reductase 1(Leishmania major)
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398393(CHEMBL2178599)
Affinity DataKi:  390nMAssay Description:Inhibition of Leishmania major PTR1 by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50443313(CHEMBL3088233)
Affinity DataKi:  390nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448343(CHEMBL3121447)
Affinity DataKi:  510nMAssay Description:Competitive inhibition of human thymidylate synthase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398388(CHEMBL2178604)
Affinity DataKi:  590nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  600nMAssay Description:Inhibition of human TS by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetThymidylate synthase(Lactobacillus casei)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM18763(1,8-naphthalein derivative, 10 | 4,4-bis(3-chloro-...)
Affinity DataKi:  700nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50398394(CHEMBL1232702)
Affinity DataKi:  800nMAssay Description:Inhibition of human DHFR by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50077844(3,3-Bis-(4-hydroxy-phenyl)-3H-isobenzofuran-1-one ...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
TargetThymidylate synthase(Lactobacillus casei)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50443314(CHEMBL3088232)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399277(CHEMBL2180553)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human thymidylate synthase expressed in Escherichia coli incubated for 1 hr using varying mTHF levels by spectrophotometry based Linewe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Enterococcus faecalis)
Universita Degli Studi Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50077844(3,3-Bis-(4-hydroxy-phenyl)-3H-isobenzofuran-1-one ...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Enterococcus faecalis thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Enterococcus faecalis)
Universita Degli Studi Di Modena E Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50350126(CHEMBL1231545)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Enterococcus faecalis thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448350(CHEMBL3121448)
Affinity DataKi:  2.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448342(CHEMBL3121450)
Affinity DataKi:  2.38E+3nMAssay Description:Competitive inhibition of human thymidylate synthase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399277(CHEMBL2180553)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human thymidylate synthase expressed in Escherichia coli incubated for 1 hr using varying dUMP levels by spectrophotometry based Linewe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50350142(CHEMBL1814081)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50350141(CHEMBL1814090)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50350140(CHEMBL1814080)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50350126(CHEMBL1231545)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448365(CHEMBL3121460)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448359(CHEMBL3121468)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448358(CHEMBL3121469)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448352(CHEMBL3121445)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448348(CHEMBL3121451)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448346(CHEMBL3121454)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448345(CHEMBL3121457)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448364(CHEMBL3121461)
Affinity DataKi:  3.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50350148(CHEMBL1814095)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthase using N5,N10-methylene tetrahydrofolate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50443314(CHEMBL3088232)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448341(CHEMBL3121453)
Affinity DataKi:  3.56E+3nMAssay Description:Competitive inhibition of human thymidylate synthase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448351(CHEMBL3121446)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448354(CHEMBL3121443)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448360(CHEMBL3121467)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448349(CHEMBL3121449)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448344(CHEMBL3121462)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Universita` Degli Studi Di Sassari

Curated by ChEMBL
LigandPNGBDBM50448340(CHEMBL3121455)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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