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Found 35 with Last Name = 'lui' and Initial = 'a'
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301911(CHEMBL583269 | N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301902(CHEMBL571825 | N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301903(CHEMBL569120 | N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301914(CHEMBL570249 | N-{2-Acetyl-3-[(S)-5-tert-butyl-1-(...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301901(CHEMBL570934 | N-{3-[(S)-5-tert-Butyl-1-(3-chloro-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301906(CHEMBL571606 | N-{3-[(S)-5-tert-Butyl-4-hydroxy-1-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301913(CHEMBL571564 | N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301900(CHEMBL568894 | N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301899(CHEMBL585384 | N-[3-((S)-1-Benzyl-5-tert-butyl-4-h...)
Affinity DataIC50:  8nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301907(CHEMBL572246 | N-{3-[(S)-5-tert-Butyl-1-(3,3-dimet...)
Affinity DataIC50:  8nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301916(CHEMBL585715 | N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301912(CHEMBL584537 | N-{3-[(S)-5-tert-Butyl-1-(4-fluoro-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301915(3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301904(CHEMBL569360 | N-{3-[(S)-5-tert-Butyl-1-(2,4-diflu...)
Affinity DataIC50:  13nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301917(CHEMBL585383 | N-{3-[(5S)-5-(1,1-dimethylpropyl)-1...)
Affinity DataIC50:  13nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301905(CHEMBL569361 | N-{3-[(S)-5-tert-Butyl-1-(5-fluoro-...)
Affinity DataIC50:  42nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301908((S)-5-tert-Butyl-1-(4-fluoro-benzyl)-3-(7-fluoro-1...)
Affinity DataIC50:  338nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301909(3-[(S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50301910((S)-5-tert-Butyl-1-(4-fluoro-benzyl)-4-hydroxy-3-(...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of HSV 1b con1 NS5B polymerase assessed as [3H]UTP incorporation into acid insoluble RNA productMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441246(CHEMBL2431456)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441246(CHEMBL2431456)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441246(CHEMBL2431456)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2-microglobulin(Homo sapiens (Human))
University of Pavia

LigandPNGBDBM52947((2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methyl...)
Affinity DataIC50:  4.70E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2-microglobulin(Homo sapiens (Human))
University of Pavia

LigandPNGBDBM92397(4-epi-oxytetracycline)
Affinity DataIC50:  4.90E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441245(CHEMBL2431365)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441245(CHEMBL2431365)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50441245(CHEMBL2431365)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2-microglobulin(Homo sapiens (Human))
University of Pavia

LigandPNGBDBM37536((2E,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methyl...)
Affinity DataIC50:  6.30E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2-microglobulin(Homo sapiens (Human))
University of Pavia

LigandPNGBDBM55038((2E,4S,4aR,5S,5aR,12aS)-2-[amino(hydroxy)methylene...)
Affinity DataIC50:  6.90E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2-microglobulin(Homo sapiens (Human))
University of Pavia

LigandPNGBDBM92395(Meclocycline)
Affinity DataIC50:  9.80E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2-microglobulin(Homo sapiens (Human))
University of Pavia

LigandPNGBDBM92398(Rolitetracycline)
Affinity DataIC50:  1.36E+5nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2-microglobulin(Homo sapiens (Human))
University of Pavia

LigandPNGBDBM92399(Anhydrochlortetracycline)
Affinity DataIC50:  1.36E+5nMpH: 7.4 T: 2°CAssay Description:Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNADPH oxidase organizer 1(Homo sapiens)TBA
LigandPNGBDBM50614675(CHEMBL5271171)
Affinity DataKd:  2nMAssay Description:Inhibition of 6His tagged NOXO1 (149 to 286 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as apparent dissociation con...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

Curated by ChEMBL
LigandPNGBDBM50503349(CHEMBL4476817)
Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to human 15N-labeled STEP PTP domain (281 to 563 residues) expressed in Escherichia coli OD2 by 1H,15N TROSY NMR spectral analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

Curated by ChEMBL
LigandPNGBDBM50503349(CHEMBL4476817)
Affinity DataKd:  8.00E+5nMAssay Description:Binding affinity to human STEP PTP domain (281 to 563 residues) expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB