Found 41 with Last Name = 'mangindaan' and Initial = 're' 
Affinity DataIC50: 32nMAssay Description:Inhibition of macrophage ACAT (unknown origin)More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of 20s constitutive proteasome beta5 chymotrypsin-like activity in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of 20s immunoproteasome LMP2 in human erythrocytes using Ac-Pro-Ala-Leu-MCA as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of 20s immunoproteasome LMP7 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta5 chymotrypsin-like activity in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubat...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of FLAG-tagged ubiquitin-activating enzyme E1 assessed as inhibition of GST-ubiquitin/FLAG-E1 intermediate formation by Western blot analy...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant His6-tagged human USP7 expressed in insect expression system using ubiquitin-Rh110 as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant His6-tagged human USP7 expressed in insect expression system using ubiquitin-Rh110 as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of macrophage ACAT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of 20s immunoproteasome LMP2 in human erythrocytes using Ac-Pro-Ala-Leu-MCA as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of recombinant His6-tagged human USP7 expressed in insect expression system using ubiquitin-Rh110 as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of 20s immunoproteasome LMP7 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant His6-tagged human USP7 expressed in insect expression system using ubiquitin-Rh110 as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Non-competitive inhibition of human microsomal ACAT2 overexpressed in CHO cells using [14C]oleoyl-CoA as substrate assessed as formation of cholester...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of ACAT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Non-competitive inhibition of human microsomal ACAT1 overexpressed in CHO cells using [14C]oleoyl-CoA as substrate assessed as formation of cholester...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta2 trypsin-like activity in human erythrocytes using Boc-Leu-Arg-Arg-MCA as substrate preincubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Non-competitive inhibition of microsomal ACAT in human MDM using [14C]oleoyl-CoA as substrate assessed as formation of cholesteryl [14C]-oleate after...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 20s immunoproteasome MECL1 in human erythrocytes using Suc-Leu-Leu-ValTyr-MCA as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of ACAT2 in human MDM assessed as inhibition of acetylated LDL-induced cholesterol ester accumulation after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tohoku Pharmaceutical University
Curated by ChEMBL
Tohoku Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 21(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of core catalytic domain of USP21 (unknown origin) using ubiquitin-Rh110 as substrateMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of ACAT1 in human MDM assessed as inhibition of acetylated LDL-induced cholesterol ester accumulation after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of USP7 (unknown origin) using ubiquitin-EKL as substrateMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of recombinant fluorescein-tagged E1 assessed as inhibition of ubiquitin-E1 adduct formation incubated for 15 mins prior to ATP addition m...More data for this Ligand-Target Pair
Affinity DataIC50: >3.16E+4nMAssay Description:Inhibition of core catalytic domain of SENP1 (unknown origin) using SUMO3-EKL as substrateMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 2(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: >3.16E+4nMAssay Description:Inhibition of core catalytic domain of USP2 (unknown origin) using diubiquitin IQF K4804 as substrateMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 8(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: >3.16E+4nMAssay Description:Inhibition of core catalytic domain of USP8 (unknown origin) using ubiquitin-Rh110 as substrateMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of FLAG-tagged ubiquitin-activating enzyme E1 assessed as inhibition of GST-ubiquitin/FLAG-E1 intermediate formation by Western blot analy...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Kumamoto University
Curated by ChEMBL
Kumamoto University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of ubiquitin-activating enzyme E1More data for this Ligand-Target Pair
