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Found 179 with Last Name = 'menke' and Initial = 'jg'
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167698(13-hydroxy-2,6-dimethyl-(2S,7R)-tricyclo[8.4.0.02,...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167697((4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,1...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167697((4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,1...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167697((4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,1...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167697((4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,1...)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-alpha in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167694(2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8....)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167694(2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8....)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167694(2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8....)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167694(2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8....)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-alpha in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167698(13-hydroxy-2,6-dimethyl-(2S,7R)-tricyclo[8.4.0.02,...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-alpha in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167700((1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9...)
Affinity DataIC50:  12nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167700((1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9...)
Affinity DataIC50:  14nMAssay Description:Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172204((1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018(2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benz...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167695(13-[13-hydroxy-2,6-dimethyl-(2S,6S,7R)-tricyclo[8....)
Affinity DataIC50:  29nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172191(3-[((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126018(2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benz...)
Affinity DataIC50:  35nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-alpha in SPA assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172204((1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167699(1-((9R,10S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,1...)
Affinity DataIC50:  67nMAssay Description:Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167695(13-[13-hydroxy-2,6-dimethyl-(2S,6S,7R)-tricyclo[8....)
Affinity DataIC50:  90nMAssay Description:Effective concentration against liver X receptor-alpha in HEK293 cell transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172206((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172188((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172185((1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172199(1-Phenyl-cyclohexanecarboxylic acid ((1S,4aS,10aR)...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172186((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-oc...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172188((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  130nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172200((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167699(1-((9R,10S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,1...)
Affinity DataIC50:  163nMAssay Description:Displacement of [3H2]-F3-methyl AA (1) from liver X receptor-beta in SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172200((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172195(((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-o...)
Affinity DataIC50:  180nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172206((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  180nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172185((1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9...)
Affinity DataIC50:  190nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172192((Dodecahydro-carbazol-9-yl)-((1S,4aS,10aR)-6-hydro...)
Affinity DataIC50:  190nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172195(((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-o...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172190((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172186((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-oc...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172190((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172207(Adamantane-1-carboxylic acid ((1S,4aS,10aR)-1,4a-d...)
Affinity DataIC50:  290nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172207(Adamantane-1-carboxylic acid ((1S,4aS,10aR)-1,4a-d...)
Affinity DataIC50:  290nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172192((Dodecahydro-carbazol-9-yl)-((1S,4aS,10aR)-6-hydro...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172197((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  310nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172197((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  350nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172189(((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-o...)
Affinity DataIC50:  360nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172189(((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-o...)
Affinity DataIC50:  370nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172199(1-Phenyl-cyclohexanecarboxylic acid ((1S,4aS,10aR)...)
Affinity DataIC50:  420nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172203((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-oc...)
Affinity DataIC50:  420nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172203((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-oc...)
Affinity DataIC50:  490nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172198(2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetrad...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172191(3-[((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,...)
Affinity DataIC50:  530nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172198(2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetrad...)
Affinity DataIC50:  750nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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