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Found 29 with Last Name = 'miller' and Initial = 'jh'
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  0.520nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM86231(ATR | ATROPINE | Atropine,(-) | CAS_51-55-8 | CHEM...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50176065(4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidini...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
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LigandPNGBDBM81800(CAS_57558-44-8 | NSC_42470 | Secoverine)
Affinity DataKi:  5.90nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM81800(CAS_57558-44-8 | NSC_42470 | Secoverine)
Affinity DataKi:  7.80nMMore data for this Ligand-Target Pair
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LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
In DepthDetails PubMed
LigandPNGBDBM81799(CAS_98299-40-2 | HHSiD | NSC_3602 | hexahydrosilad...)
Affinity DataKi:  47nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM81799(CAS_98299-40-2 | HHSiD | NSC_3602 | hexahydrosilad...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  214nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  410nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  600nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50018056((AF-DX 116) 11-[2-(2-Diethylaminomethyl-piperidin-...)
Affinity DataKi:  614nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50018056((AF-DX 116) 11-[2-(2-Diethylaminomethyl-piperidin-...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  44.5nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  45nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50008685(1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3...)
Affinity DataIC50:  900nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50008685(1-Amino-13-ethylidene-11-methyl-6-aza-tricyclo[7.3...)
Affinity DataIC50:  900nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50008689(1-Amino-13-ethylidene-6-aza-tricyclo[7.3.1.0*2,7*]...)
Affinity DataIC50:  9.82E+3nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50008684(5-Amino-6-ethylidene-5-methyl-5,6,7,8-tetrahydro-1...)
Affinity DataIC50:  3.38E+5nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50008687(5-Dimethylaminomethyl-1H-pyridin-2-one | CHEMBL323...)
Affinity DataIC50: >9.00E+5nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50008688(5-Aminomethyl-1H-pyridin-2-one | CHEMBL323807)
Affinity DataIC50: >9.00E+5nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  3nMAssay Description:Dissociation constant for the blocking of cardiac muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  4.40E+3nMAssay Description:Dissociation constant of the compound for human Muscarinic acetylcholine receptor M2 was determined.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  1.21E+3nMAssay Description:Dissociation constant for the blocking of brainstem muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  11nMAssay Description:Potency of the compound assessed to inhibit cAMP levels in N1E-115 neuroblastoma cells, for blocking oxotremorine-M in functional assay for Muscarini...More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  6.90nMAssay Description:Dissociation constant for the blocking of heart muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  4.60nMAssay Description:Dissociation constant for the blocking of brainstem muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50076089((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methy...)
Affinity DataKd:  5.40nMAssay Description:Potency of the compound assessed to inhibit cAMP levels in rat striatum, for blocking oxotremorine-M, in functional assay for Muscarinic acetylcholin...More data for this Ligand-Target Pair
In DepthDetails Article
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280521((4R,5S)-5-Methyl-4-[(E)-3-((R)-1-methyl-piperidin-...)
Affinity DataKd:  9.70E+3nMAssay Description:Dissociation constant of the compound for human Muscarinic acetylcholine receptor M1 was determined.More data for this Ligand-Target Pair
In DepthDetails Article