Found 13 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M2' and Ligand = 'BDBM50076089' TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:In vitro inhibitory activity against cloned human M2 muscarinic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Binding affinity against the muscarinic M2 (brainstem) subtype was evaluated using [3H]quinuclidinyl benzilateMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity against human muscarine receptor (hM2) cloned in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Binding affinity against human muscarine receptor (hM2) cloned in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Affinity for Muscarinic acetylcholine receptor M2 expressed in CHO cells by [3H]NMS displacement.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:The compound was tested in vitro for binding activity against M2 muscarinic receptor in homogenates of the brainstem of rat using [3H]quinuclidinyl b...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Binding affinity towards human muscarinic M2 receptor in CHO-KI cells using [3H]- QNB as radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m2 by displacement of [3H]NMS binding using membranes from transfected chinese hamste...More data for this Ligand-Target Pair
Affinity DataKd: 4.60nMAssay Description:Dissociation constant for the blocking of brainstem muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
Affinity DataKd: 6.90nMAssay Description:Dissociation constant for the blocking of heart muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity against M2 receptor in rat brainstem cells using radioligand [3H]-quinuclidinyl benzilate ([3H]-QNB)More data for this Ligand-Target Pair
Affinity DataKd: 9.10nMAssay Description:Displacement of [3H]-QNB from rat brain stem muscarinic receptor 2 (M2)More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Dissociation constant for the blocking of cardiac muscarinic M2 receptor was reported.More data for this Ligand-Target Pair
