TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataKi: 68nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataKi: 470nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0290nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.180nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Friedrich Miescher Institute For Biomedical Research
Friedrich Miescher Institute For Biomedical Research
Affinity DataIC50: 4.67nMAssay Description:. Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...More data for this Ligand-Target Pair
TargetHistone deacetylase 6 [25-831](Danio rerio (Zebrafish))
Friedrich Miescher Institute For Biomedical Research
Friedrich Miescher Institute For Biomedical Research
Affinity DataIC50: 5.45nMAssay Description:. Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Friedrich Miescher Institute For Biomedical Research
Friedrich Miescher Institute For Biomedical Research
Affinity DataIC50: 5.76nMAssay Description:. Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Friedrich Miescher Institute For Biomedical Research
Friedrich Miescher Institute For Biomedical Research
Affinity DataIC50: 8.09nMAssay Description:. Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...More data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6 [25-831](Danio rerio (Zebrafish))
Friedrich Miescher Institute For Biomedical Research
Friedrich Miescher Institute For Biomedical Research
Affinity DataIC50: 9.88nMAssay Description:. Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Friedrich Miescher Institute For Biomedical Research
Friedrich Miescher Institute For Biomedical Research
Affinity DataIC50: 11.1nMAssay Description:. Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Friedrich Miescher Institute For Biomedical Research
Friedrich Miescher Institute For Biomedical Research
Affinity DataIC50: 17.8nMAssay Description:. Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLCMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of ACE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Friedrich Miescher Institute For Biomedical Research
Friedrich Miescher Institute For Biomedical Research
Affinity DataIC50: 29.2nMAssay Description:. Enzymatic characterization (Km determinations, Supplementary Fig. 3C) of zebrafish HDAC6 proteins (CD1-CD2; CD1H193A-CD2; CD1CD2H574A; CD1H193A- CD...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLCMore data for this Ligand-Target Pair