Compile Data Set for Download or QSAR
maximum 50k data
Found 144 with Last Name = 'miyata' and Initial = 'h'
TargetBeta-2 adrenergic receptor(Canis familiaris)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataIC50:  0.100nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. IC50, the mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554513((5RS)-2-(4-Methylbenzyl)-3-oxo-5-(pyrrolidin-1-ylc...)
Affinity DataIC50:  0.160nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554510((5RS)-7-(Cyclopropylcarbonyl)-2-(4-methylbenzyl)-5...)
Affinity DataIC50:  0.170nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554533((5RS)-2-[(5-Chloropyridin-3-yl)methyl]-5-{[(3S)-3-...)
Affinity DataIC50:  0.200nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554514((5RS)-7-Methyl-2-(4-methylbenzyl)-5-(pyrrolidin-1-...)
Affinity DataIC50:  0.220nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554517((5RS)—N-Cyclopropyl-2-(4-methylbenzyl)-3-oxo-...)
Affinity DataIC50:  0.325nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554517((5RS)—N-Cyclopropyl-2-(4-methylbenzyl)-3-oxo-...)
Affinity DataIC50:  0.350nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554514((5RS)-7-Methyl-2-(4-methylbenzyl)-5-(pyrrolidin-1-...)
Affinity DataIC50:  0.370nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554501(US11337973, Example 5 | tert-Butyl (5RS)-5-{[(3S)-...)
Affinity DataIC50:  0.510nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554520((5RS)-2-(4-Methylbenzyl)-3-oxo-5-(pyrrolidin-1-ylc...)
Affinity DataIC50:  0.660nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554502((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...)
Affinity DataIC50:  0.670nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554521((5RS)-2-{[3-Chloro-4-(trifluoromethyl)pyridin-2-yl...)
Affinity DataIC50:  0.730nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554510((5RS)-7-(Cyclopropylcarbonyl)-2-(4-methylbenzyl)-5...)
Affinity DataIC50:  0.870nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554522((5RS)—N-(3,4-Dichlorophenyl)-2-(4-methylbenzy...)
Affinity DataIC50:  0.870nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554507((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-7...)
Affinity DataIC50:  0.935nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554497(US11337973, Example 1 | tert-Butyl (5RS)-2-(4-meth...)
Affinity DataIC50:  0.970nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554533((5RS)-2-[(5-Chloropyridin-3-yl)methyl]-5-{[(3S)-3-...)
Affinity DataIC50:  1.20nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554505(US11337973, Example 9 | tert-Butyl (5RS)-5-{[(3S)-...)
Affinity DataIC50:  1.27nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554507((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-7...)
Affinity DataIC50:  1.40nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554523((5RS)—N-(2,2-Difluoroethyl)-2-(4-methylbenzyl...)
Affinity DataIC50:  1.70nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554524((5RS)—N-tert-Butyl-2-(4-methylbenzyl)-3-oxo-5...)
Affinity DataIC50:  2.20nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554525((5RS)-2-{[3-Chloro-4-(trifluoromethyl)pyridin-2-yl...)
Affinity DataIC50:  2.40nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554526((5RS)-7-Isobutyl-2-(4-methylbenzyl)-5-(pyrrolidin-...)
Affinity DataIC50:  2.80nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554506((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...)
Affinity DataIC50:  3nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554498((5RS)-2-(4-Methylbenzyl)-5-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50:  3.05nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554502((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...)
Affinity DataIC50:  3.5nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554527((5RS)-7-Cyclobutyl-2-(4-methylbenzyl)-5-(pyrrolidi...)
Affinity DataIC50:  4nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554531((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-7...)
Affinity DataIC50:  4.20nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554528((5RS)-2-(4-Methylbenzyl)-5-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50:  5.10nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554500((5RS)-2-{[3-Chloro-4-(trifluoromethyl)pyridin-2-yl...)
Affinity DataIC50:  5.15nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554499(US11337973, Example 3 | tert-Butyl (5RS)-2-{[3-chl...)
Affinity DataIC50:  5.45nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50002133((+/-)-2-(4-((R)-2-((R)-2-(3-chlorophenyl)-2-hydrox...)
Affinity DataIC50:  9.12nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM97162(MLS002153782 | RITODRINE | RITODRINE HYDROCHLORIDE...)
Affinity DataIC50:  24.0nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554532(US11337973, Example 37 | [(5-Chloropyridin-3-yl)me...)
Affinity DataIC50:  47nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50409479(CHEMBL32933)
Affinity DataIC50:  61.7nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554510((5RS)-7-(Cyclopropylcarbonyl)-2-(4-methylbenzyl)-5...)
Affinity DataIC50:  72.5nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554533((5RS)-2-[(5-Chloropyridin-3-yl)methyl]-5-{[(3S)-3-...)
Affinity DataIC50:  88.5nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of COX1 from ram seminal vesicles by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554517((5RS)—N-Cyclopropyl-2-(4-methylbenzyl)-3-oxo-...)
Affinity DataIC50:  120nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554514((5RS)-7-Methyl-2-(4-methylbenzyl)-5-(pyrrolidin-1-...)
Affinity DataIC50:  146nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50292595(25-hydroxy-3alpha-acetoxylanost-8-en-21-oicacid 21...)
Affinity DataIC50:  150nMAssay Description:Inhibition of sheep placental COX2 by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50409484(CHEMBL32470)
Affinity DataIC50:  251nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554529((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...)
Affinity DataIC50:  280nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50409476(CHEMBL289670)
Affinity DataIC50:  282nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50073710(4-[5-(4-Benzhydryl-piperazin-1-yl)-pentyloxy]-2,3,...)
Affinity DataIC50:  351nMAssay Description:Evaluated for inhibitory activity against RBL-1 cell 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50073709(4-[4-(4-Benzhydryl-piperazin-1-yl)-butoxy]-2,3,6-t...)
Affinity DataIC50:  358nMAssay Description:Evaluated for inhibitory activity against RBL-1 cell 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554530((5RS)-7-(Cyclopropylcarbonyl)-5-{[(3S)-3-fluoropyr...)
Affinity DataIC50:  415nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50073707(4-[3-(4-Benzhydryl-piperazin-1-yl)-propoxy]-2,3,6-...)
Affinity DataIC50:  426nMAssay Description:Evaluated for inhibitory activity against RBL-1 cell 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554502((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...)
Affinity DataIC50:  455nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50073711(4-[6-(4-Benzhydryl-piperazin-1-yl)-hexyloxy]-2,3,6...)
Affinity DataIC50:  526nMAssay Description:Evaluated for inhibitory activity against RBL-1 cell 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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