Affinity DataKi: 1.20nMAssay Description:Binding affinity to rat A2A adenosine receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.73nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of MRS5346 from C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pich...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 9.70nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity to rat A2A adenosine receptorMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of MRS5346 from C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pich...More data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Inhibition of factor 10a in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of MRS5346 from C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pich...More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 481nMAssay Description:Displacement of MRS5346 from C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pich...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.52E+3nMAssay Description:Displacement of MRS5346 from C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pich...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.30E+3nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human thrombin by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human thrombin by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human thrombin by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+4nMAssay Description:Inhibition of human factor 10a by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.60E+4nMAssay Description:Inhibition of human thrombin by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.78E+4nMAssay Description:Inhibition of human thrombin by Dixon-plot methodMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Agonistic activity for Beta-2 adrenergic receptor was assessed by it's inhibitory effect on spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. IC50, the mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 0.930nMAssay Description:Inhibition of wild type human N-terminal GST-fusion tagged TRKB kinase domain (456 to 822 residues) expressed in baculovirus expression system by HTR...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of wild type human His-tagged TRKA kinase domain (441 to 796 residues) expressed in baculovirus expression system by HTRF assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of juxtamembrane region deficient recombinant human N-terminal His6-tagged/GST-tagged TrkA (498 to 796 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of TRKA E735A mutant (unknown origin) expressed in baculovirus infected sf9 cells assessed as kinase domain dimerization by HTRF assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of juxtamembrane region containing recombinant human N-terminal His6-tagged/GST-tagged TrkA (473 to 796 residues) expressed in baculovirus...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of juxtamembrane region containing recombinant human N-terminal His6-tagged/GST-tagged TrkA (473 to 796 residues) expressed in baculovirus...More data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human TrkB expressed in DHFR deficient CHO cells assessed as inhibition of human brain-derived neurotrophic factor-induced ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human TrkC expressed in DHFR deficient CHO cells assessed as inhibition of human neurotrophin-3-induced calcium influx by F...More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of juxtamembrane region deficient recombinant human N-terminal His6-tagged/GST-tagged TrkA (498 to 796 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Agonistic activity for Beta-2 adrenergic receptor was assessed by it's inhibitory effect on spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 9.12nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Osaka Prefecture University
Curated by ChEMBL
Osaka Prefecture University
Curated by ChEMBL
Affinity DataIC50: 9.90nMAssay Description:Inhibition of recombinant human TrkA expressed in DHFR deficient CHO cells assessed as inhibition of human beta-nerve growth factor-induced calcium i...More data for this Ligand-Target Pair