TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00230nM ΔG°: -69.1kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00550nM ΔG°: -66.9kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DataKi: 0.00680nM ΔG°: -66.3kJ/molepH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 0.497nMAssay Description:Inhibition of vitronectin binding to integrin alphaVbeta3 in HDF pretreated for 20 mins followed by vitronectin addition measured after 40 mins by cr...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of vitronectin binding to integrin alphaVbeta3 in HDF pretreated for 20 mins followed by vitronectin addition measured after 40 mins by cr...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda
National Cancer Institute-Bethesda
Affinity DatapH: 6.2 T: 2°CAssay Description:Inhibition constants were determined by a fluorometric assay with the fluorogenic substrate Arg-Glu(EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Lys(DABCYL)-Ar...More data for this Ligand-Target Pair