TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 91nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR (unknown origin)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR from rat hippocampusMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR from rat hippocampusMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.60E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR from rat hippocampusMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 2.90E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR from rat hippocampusMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 4.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR from rat hippocampusMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.00E+5nMAssay Description:Displacement of [3H]methyllycaconitine from alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human plasma AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human plasma AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of bovine erythrocyte AChE using acetylthiocholine iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]-methylscopolamine binding to muscarinic M3 receptor in submaxillary salivary glands of rats.More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Displacement of [3H]-pirenzepine binding to muscarinic M1 receptor in brain cortex of rat.More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of bovine erythrocyte AChE using acetylthiocholine iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(RAT)
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Dipartimento Di Scienze Farmaceutiche - Università
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Displacement of [3H]-methylscopolamine binding to muscarinic M2 receptor in rat heart.More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocoline iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair