Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.117nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.171nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.281nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.296nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.306nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucoseMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Candida albicans ATCC 90028 glucan synthase at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.503nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.877nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucoseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serumMore data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Candida albicans ATCC 90028 glucan synthase at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 20% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.14nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.14nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 50% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 50% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of FKS1 from Candida krusei 98 isolateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082More data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 50% human serumMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Neosartorya fumigata)
Umdnj-New Jersey Medical School
Curated by ChEMBL
Umdnj-New Jersey Medical School
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase EMFR-S678P mutant from Aspergillus fumigatus assessed as incorporation of [3H]glucoseMore data for this Ligand-Target Pair
Affinity DataIC50: 13.4nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 13.4nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314More data for this Ligand-Target Pair
Affinity DataIC50: 14.2nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 14.8nMAssay Description:Inhibition of Candida albicans ATCC 90028 glucan synthase at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314More data for this Ligand-Target Pair
Affinity DataIC50: 16.2nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082More data for this Ligand-Target Pair
Affinity DataIC50: 16.3nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 16.4nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 20% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 18.7nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 21.2nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314More data for this Ligand-Target Pair
Affinity DataIC50: 21.7nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 50% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 22.4nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 24.7nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 25.7nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 25.8nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 50% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 10% human serumMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 27.7nMAssay Description:Inhibition of Candida tropicalis T26 blood stream isolate glucan synthase subunit FKS1p with LLTLSLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Neosartorya fumigata)
Umdnj-New Jersey Medical School
Curated by ChEMBL
Umdnj-New Jersey Medical School
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase EMFR-S678P mutant from Aspergillus fumigatus assessed as incorporation of [3H]glucoseMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 39.4nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 20% human serumMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 39.9nMAssay Description:Inhibition of Candida glabrata isolate 5416 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p W1375L mutantMore data for this Ligand-Target Pair