Found 32 Enz. Inhib. hit(s) with Target = '1,3-beta-glucan synthase' and Ligand = 'BDBM50417554' Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.281nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 0.503nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.877nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucoseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.14nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 10% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.14nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 13.4nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314More data for this Ligand-Target Pair
Affinity DataIC50: 16.2nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082More data for this Ligand-Target Pair
Affinity DataIC50: 16.3nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 16.4nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 20% serumMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 21.7nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 90028 in presence of 50% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 25.8nMAssay Description:Inhibition of glucan synthase in Candida albicans 36082 assessed as incorporation of [3H]uridine diphosphoglucose in presence of 50% serumMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 27.7nMAssay Description:Inhibition of Candida tropicalis T26 blood stream isolate glucan synthase subunit FKS1p with LLTLSLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Neosartorya fumigata)
Umdnj-New Jersey Medical School
Curated by ChEMBL
Umdnj-New Jersey Medical School
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of 1,3-beta-D-glucan synthase EMFR-S678P mutant from Aspergillus fumigatus assessed as incorporation of [3H]glucoseMore data for this Ligand-Target Pair
Affinity DataIC50: 62.7nMAssay Description:Inhibition of glucan synthase in Candida albicans ATCC 36082 in presence of 20% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 65.5nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 20% human serumMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 74.7nMAssay Description:Inhibition of Candida glabrata isolate 5416 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p W1375L mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 75.9nMAssay Description:Inhibition of Candida glabrata isolate 234 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659V mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 78.1nMAssay Description:Inhibition of glucan synthase in Candida albicans SC5314 in presence of 50% human serumMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 87.3nMAssay Description:Inhibition of Candida glabrata isolate 51916 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p P667T mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 89.3nMAssay Description:Inhibition of Candida glabrata isolate 21900 1,3-beta-D-glucan synthase Fks1p D632G mutant/wild type Fks2pMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of Candida glabrata isolate 42997 1,3-beta-D-glucan synthase Fks1p F625S mutant/wild type Fks2pMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 111nMAssay Description:Inhibition of Candida glabrata isolate 42031 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666E mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 132nMAssay Description:Inhibition of Candida glabrata isolate 3169 1,3-beta-D-glucan synthase Fks1p D632E mutant/wild type Fks2pMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 154nMAssay Description:Inhibition of Candida glabrata isolate 41400 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p D666G mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 204nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida tropicalis)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 357nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 752nMAssay Description:Inhibition of Candida glabrata isolate 41026 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p F659S mutantMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of Candida glabrata isolate 5847 1,3-beta-D-glucan synthase Fks1p S629P mutant/wild type Fks2pMore data for this Ligand-Target Pair
Target1,3-beta-glucan synthase(Candida glabrata)
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
University Of Medicine And Dentistry Of New Jersey
Curated by ChEMBL
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of Candida glabrata isolate 3830 1,3-beta-D-glucan synthase wild type Fks1p/Fks2p S663P mutantMore data for this Ligand-Target Pair
