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Found 220 with Last Name = 'pohanka' and Initial = 'm'
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50336116(Ambenonium dichloride | CHEMBL1669479)
Affinity DataKi:  5nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50336116(Ambenonium dichloride | CHEMBL1669479)
Affinity DataKi:  6nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  10nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119798(1,11-bis(pyridinium)-undecane dibromide | 1,11-di(...)
Affinity DataKi:  20nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by noncompetitive Lineweaver-burk plot analysis for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119798(1,11-bis(pyridinium)-undecane dibromide | 1,11-di(...)
Affinity DataKi:  30nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by noncompetitive Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataKi:  50nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334300(1,8-bis(4-tert.butylpyridinium)-oct-1,8-diyl dibro...)
Affinity DataKi:  90nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334303(1,1'-bis(4-tert.butylpyridinium)-naphtyl-3,6-dimet...)
Affinity DataKi:  100nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334303(1,1'-bis(4-tert.butylpyridinium)-naphtyl-3,6-dimet...)
Affinity DataKi:  100nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50313093(1,1'-bis(pyridinium)-naphtyl-3,6-dimethylene dibro...)
Affinity DataKi:  140nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by noncompetitive Lineweaver-burk plot analysis for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50313093(1,1'-bis(pyridinium)-naphtyl-3,6-dimethylene dibro...)
Affinity DataKi:  140nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by noncompetitive Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334300(1,8-bis(4-tert.butylpyridinium)-oct-1,8-diyl dibro...)
Affinity DataKi:  200nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119786(1,8-di(2-isoquinoliniumyl)octane; with diiodide io...)
Affinity DataKi:  620nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50336130(1,10-Bis(isoquinolinium)-naphtyl-3,6-dimethylenyld...)
Affinity DataKi:  750nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM120262(EDROPHONIUM BROMIDE | EDROPHONIUM CHLORIDE | Edrop...)
Affinity DataKi:  790nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119786(1,8-di(2-isoquinoliniumyl)octane; with diiodide io...)
Affinity DataKi:  980nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50336130(1,10-Bis(isoquinolinium)-naphtyl-3,6-dimethylenyld...)
Affinity DataKi:  1.25E+3nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM120262(EDROPHONIUM BROMIDE | EDROPHONIUM CHLORIDE | Edrop...)
Affinity DataKi:  4.80E+3nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataKi:  2.47E+4nMAssay Description:Dissociation constant for enzyme-inhibitor complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataKi:  2.47E+4nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataKi:  1.21E+7nMAssay Description:Dissociation constant for enzyme-inhibitor-substrate complex of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM8958(10-(2-diethylaminopropyl)phenothiazine | CHEMBL120...)
Affinity DataKi:  1.21E+7nMAssay Description:Inhibition of human recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complex by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50336116(Ambenonium dichloride | CHEMBL1669479)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334300(1,8-bis(4-tert.butylpyridinium)-oct-1,8-diyl dibro...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119786(1,8-di(2-isoquinoliniumyl)octane; with diiodide io...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50304127(1,12-Bis-(4-tert-butylpyridinium)dodecane dibromid...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334301(1,10-bis(4-tert.butylpyridinium)-dec-1,10-diyl dib...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334302(1,7-bis(4-tert.butylpyridinium)-hept-1,7-diyl dibr...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334300(1,8-bis(4-tert.butylpyridinium)-oct-1,8-diyl dibro...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50304127(1,12-Bis-(4-tert-butylpyridinium)dodecane dibromid...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human plasmatic BChE after 5 minsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334303(1,1'-bis(4-tert.butylpyridinium)-naphtyl-3,6-dimet...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334304(1,11-bis(4-tert.butylpyridinium)-undec-1,11-diyl d...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM10624(1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-on...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334305(1,6-bis(4-tert.butylpyridinium)-hex-1,6-diyl dibro...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334306(1,9-bis(4-tert.butylpyridinium)-non-1,9-diyl dibro...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50327936(CHEMBL1257767 | CHEMBL1618106 | N-n-heptyl-7-metho...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human plasmatic BChE after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119777(1,9-di(2-isoquinoliniumyl)nonane; with dibromide i...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119780(1,10-di(2-isoquinoliniumyl)decane; with diiodide i...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM234372(but-(2E)-en-1,4-diyl-1,1'-bis(4-(3-phenylpropy...)
Affinity DataIC50:  50nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334301(1,10-bis(4-tert.butylpyridinium)-dec-1,10-diyl dib...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human erythrocyte AChE after 5 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119805(1,12-di(2-isoquinoliniumyl)dodecane; with dibromid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human plasmatic BChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50327935(CHEMBL1257885 | CHEMBL1618217 | N-n-hexyl-7-methox...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant AChE after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50119776(1,11-di(2-isoquinoliniumyl)undecane; with dibromid...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant AChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  100nMpH: 7.4Assay Description:Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
University Of Defence

Curated by ChEMBL
LigandPNGBDBM50334304(1,11-bis(4-tert.butylpyridinium)-undec-1,11-diyl d...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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