Found 312 with Last Name = 'ponzano' and Initial = 's' TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 4nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human spleen NAAA enzyme expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 5nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 5nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human spleen NAAA enzyme expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human spleen NAAA expressed in HEK293 cells using PAMCA as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human spleen NAAA expressed in HEK293 cells using PAMCA as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 6nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysisMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 7nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human spleen NAAA enzyme expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 7nMAssay Description:Inhibition of C-terminal His-6-tagged recombinant human spleen NAAA enzyme expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 7nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 7nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 7nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 7nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human recombinant His6-tagged NAAA expressed in HEK293 cells using 10-cis-heptadecenoylethanolamide as substrate after 30 mins by UPLC/...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 8nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 9nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 9nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human spleen NAAA expressed in HEK293 cells using PAMCA as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 12nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysisMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 14nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 14nMpH: 4.5 T: 2°CAssay Description:NAAA protein preparation (10 ug) was pre-incubated with various concentrations of test compound or vehicle control in 100 mM NaH2PO4, 100 mM Tri Sodi...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 15nMpH: 4.5Assay Description:The assay was run in Optiplate 96-wells black plates, in a total reaction volume of 200 μL. NAAA protein preparation (4.0 μg) was pre-incub...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 15.5nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 16nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Rattus norvegicus (Rat))
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 16nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human spleen NAAA expressed in HEK293 cells using PAMCA as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human spleen NAAA expressed in HEK293 cells using PAMCA as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
University of California
US Patent
University of California
US Patent
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human spleen NAAA expressed in HEK293 cells using PAMCA as substrate preincubated for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
