Compile Data Set for Download or QSAR
maximum 50k data
Found 216 with Last Name = 'puris' and Initial = 'e'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50220541(CHEMBL392158 | Fallypride | N-(((S)-1-allylpyrroli...)
Affinity DataKi:  0.0970nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50366495((+)butaclamol | CHEMBL1255588)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015491(CHEMBL3265329)
Affinity DataKi:  0.630nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.850nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50005118((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015511(CHEMBL3265049)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015527(CHEMBL3265321)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50001888((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015532(CHEMBL3265324)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015499(CHEMBL3265045)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015497(CHEMBL3265043)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015493(CHEMBL3265039)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015494(CHEMBL3265040)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015496(CHEMBL3265042)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015498(CHEMBL3265044)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121305(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  16nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121291(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  19nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM21006((2R)-5-[(diaminomethylidene)amino]-2-[(2R)-3-(meth...)
Affinity DataKi:  19nM ΔG°:  -44.1kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015492(CHEMBL3265038)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20998((2R)-5-[(diaminomethylidene)amino]-N-[(1S)-2-pheny...)
Affinity DataKi:  21nM ΔG°:  -43.8kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121299(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  21nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20997((2S)-N-[(1R)-4-[(diaminomethylidene)amino]-1-{[(1S...)
Affinity DataKi:  23nM ΔG°:  -43.6kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20999((2R)-2-[(2R)-3-(benzylsulfanyl)-2-[1-(4-phenylphen...)
Affinity DataKi:  24nM ΔG°:  -43.5kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015502(CHEMBL3265048)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015514(CHEMBL3265316)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015515(CHEMBL3265317)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015495(CHEMBL3265041)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015512(CHEMBL3265314)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015500(CHEMBL3265046)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015501(CHEMBL3265047)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015518(CHEMBL3265318)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015524(CHEMBL3265319)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20993((2R)-5-[(diaminomethylidene)amino]-N-[(1S)-2-(4-hy...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121290(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  45nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015526(CHEMBL3265320)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015530(CHEMBL3265322)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015513(CHEMBL3265315)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50015531(CHEMBL3265323)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121286(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  67nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20996((2R)-5-[(diaminomethylidene)amino]-N-[(1S)-2-(4-hy...)
Affinity DataKi:  112nM ΔG°:  -39.7kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM20995((2R)-2-[(2R)-3-(benzylsulfanyl)-2-[1-(4-phenylphen...)
Affinity DataKi:  155nM ΔG°:  -38.9kJ/molepH: 5.5 T: 2°CAssay Description:Fluorescence was monitored on a SPEX Fluorolog-2 spectrofluorometer with the excitation and emission wavelengths set at 380 and 440 nm, respectively....More data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121298(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  160nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121300(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121300(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  170nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121301(5-Amino-2-[2-(2-biphenyl-4-yl-acetylamino)-3-methy...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121292(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  210nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121288(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  210nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121295(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulfany...)
Affinity DataKi:  240nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121293(2-[2-(2-Biphenyl-4-yl-acetylamino)-3-mercapto-prop...)
Affinity DataKi:  270nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50121289(2-{2-[2-(2-Biphenyl-4-yl-acetylamino)-3-methylsulf...)
Affinity DataKi:  270nMAssay Description:Inhibitory activity against human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 216 total ) | Next | Last >>
Jump to: