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Found 572 with Last Name = 'reddy' and Initial = 'j'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339236((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339240((1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339242((1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339233((1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398563(CHEMBL2178089)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  1.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339238((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398564(CHEMBL2178087)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339237((1R,2S)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339231((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339232((1S,2R)-N-((S)-1-((2R,3R)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  4.11nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339235((1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339239((1S,2R)-N-((S)-1-((2R,3R)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  9.70nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339243((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  11.1nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50326885((S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-(2...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339241((1S,2R)-N-((S)-1-((2R,3R)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  33.9nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339234((1S,2R)-N-((S)-1-((2R,3R)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  34.6nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398562(CHEMBL2178090)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339236((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  96nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339233((1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  123nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339240((1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339230((1R,2S)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  143nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339239((1S,2R)-N-((S)-1-((2R,3R)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  198nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339232((1S,2R)-N-((S)-1-((2R,3R)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  287nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339238((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  366nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339231((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  571nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339242((1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  661nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339237((1R,2S)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  689nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398564(CHEMBL2178087)
Affinity DataKi:  1.03E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339241((1S,2R)-N-((S)-1-((2R,3R)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339235((1S,2R)-N-((S)-1-((2S,3S)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398561(CHEMBL2178088)
Affinity DataKi:  2.16E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398560(CHEMBL2178086)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339243((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  2.64E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339234((1S,2R)-N-((S)-1-((2R,3R)-1-amino-1-oxo-3-phenylbu...)
Affinity DataKi:  3.36E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  4.17E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50339230((1R,2S)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  7.82E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  8.50E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  8.77E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398563(CHEMBL2178089)
Affinity DataKi:  9.94E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398561(CHEMBL2178088)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398562(CHEMBL2178090)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50326885((S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-(2...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50398560(CHEMBL2178086)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286091((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...)
Affinity DataIC50:  0.300nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286091((R)¿N-(1-(4-aminobenzyl)-1H-pyrazol-4-yl)-9-methyl...)
Affinity DataIC50:  0.300nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA gyrase subunit B(Mycobacterium smegmatis)
Astrazeneca India

Curated by ChEMBL
LigandPNGBDBM50010376(CHEMBL3263618)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19516((2S)-N-[(3S,5E)-6-(benzenesulfonyl)-4-oxo-1-phenyl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant cathepsin S after 10 minsMore data for this Ligand-Target Pair
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