Affinity DataKi: 0.160nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Binding affinity towards Opioid receptor mu 1 by displacing [3H]DAMGO in rat brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]DAMGO from rat cortical MOR by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]DAMGO from MOP receptor expressed in CHO-K1 cells after overnight incubation by beta counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.11nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.45nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.62nMAssay Description:Displacement of [3H]-endomorphin-2 from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]endomorphin-2 from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]DAMGO from human cloned mu-opioid receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]DAMGO from rat cortex mu opioid receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.21nMAssay Description:Displacement of [3H]-DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes preincubated for 1 hr measured after 1hr by scintillation counting m...More data for this Ligand-Target Pair
Affinity DataKi: 4.55nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor in Wistar rat brain membrane after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 10.7nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity towards Opioid receptor mu 1More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [3H]-DAMGO from Wistar rat mu opioid receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.430nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [3H]DAMGO binding to Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Agonist activity at MOP receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.03nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig intestine assessed as inhibition of electrically evoked myenteric plexus longitudinal mu...More data for this Ligand-Target Pair
Affinity DataIC50: 10.1nMAssay Description:Inhibition of Opioid receptor mu 1 of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of mu opioid receptor in guinea pig ileum/longitudinal muscle with myenteric plexus assessed as inhibition of electrically-stimulated musc...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Agonist activity at mu opioid receptor in human SHSY5Y cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 36.3nMAssay Description:Inhibition of Mu opioid receptor of mouse vas deferensMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Concentration required for inhibition of [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 104nMAssay Description:Activity at mu opioid receptor in Wistar rat brain assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by liqui...More data for this Ligand-Target Pair
Affinity DataEC50: 61nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in human HEK293 cells assessed as increase in cAMP accumulation using [3H]-cAMP as ...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at mu-opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at human MOP assessed as forskolin stimulated cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) transfected in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 166nMAssay Description:Agonist activity at mu opioid receptor in rat brain membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00100nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair