Target1-phosphatidylinositol phosphodiesterase(Bacillus cereus)
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 6.40E+3nMAssay Description:Inhibition of Bacillus cereus phospholipase C by amplex red assayMore data for this Ligand-Target Pair
Target1-phosphatidylinositol phosphodiesterase(Bacillus cereus)
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of Bacillus cereus phospholipase C using L-alpha-phosphatidylcholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Target1-phosphatidylinositol phosphodiesterase(Bacillus cereus)
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataKi: 7.10E+4nMAssay Description:Inhibition of Bacillus cereus PC-phospholipase C using phosphoryl-choline as substrate by molybdenum blue dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
University Of Auckland
Curated by ChEMBL
University Of Auckland
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human TDP1 measured by real-time oligonucleotide biosensor assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant Aurora C expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant Aurora B expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human TDP1 measured by real-time oligonucleotide biosensor assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Siberian Branch Of The Russian Academy Of Science
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair