Compile Data Set for Download or QSAR
maximum 50k data
Found 277 with Last Name = 'reynisson' and Initial = 'j'
Target1-phosphatidylinositol phosphodiesterase(Bacillus cereus)
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50555554(CHEMBL4751563)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibition of Bacillus cereus phospholipase C by amplex red assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol phosphodiesterase(Bacillus cereus)
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50555553(CHEMBL4764001)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of Bacillus cereus phospholipase C using L-alpha-phosphatidylcholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1-phosphatidylinositol phosphodiesterase(Bacillus cereus)
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50555552(CHEMBL4785156)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition of Bacillus cereus PC-phospholipase C using phosphoryl-choline as substrate by molybdenum blue dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318595(6-Bromo-7-[4-(5-methyl-isoxazol-3-ylmethyl)-pipera...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50514365(CHEMBL4587036)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318610(6-Bromo-7-[4-(5-methyl-isoxazol-3-ylmethyl)-pipera...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318575(2-{4-[6-Chloro-2-(4-morpholin-4-ylmethylphenyl)-3H...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318601(4-((4-(6-Bromo-2-(4-methoxyphenyl)-3H-imidazo[4,5-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50514367(CHEMBL4581126)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318588(6-Bromo-2-(4-morpholin-4-ylmethyl-phenyl)-7-(4-pyr...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318602(4-(4-(6-Bromo-7-(4-(thiazol-4-ylmethyl)piperazin-1...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318590(4-(4-(6-Bromo-7-(4-(pyrimidin-5-ylmethyl)piperazin...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50514366(CHEMBL4447701)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318589(6-Bromo-2-(4-methoxyphenyl)-7-(4-(pyrimidin-5-ylme...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318587(6-Bromo-2-(4-methoxyphenyl)-7-(4-(pyridin-3-ylmeth...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318603(3-((4-(6-Bromo-2-(4-(piperazin-1-ylmethyl)phenyl)-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318605((4-(6-Bromo-7-(4-((5-methylisoxazol-3-yl)methyl)pi...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318609(3-((4-(6-Bromo-2-(4-(piperazin-1-yl)phenyl)-3H-imi...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318597(3-((4-(6-Chloro-2-(4-(4-methylpiperazin-1-yl)pheny...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318611(3-((4-(2-(4-((1H-Pyrazol-1-yl)methyl)phenyl)-6-chl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318592(6-BROMO-7-[4-(4-CHLOROBENZYL)PIPERAZIN-1-YL]-2-[4-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318604(1-(4-(6-Bromo-7-(4-((5-methylisoxazol-3-yl)methyl)...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318596(3-((4-(6-Bromo-2-(4-(4-methylpiperazin-1-yl)phenyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398609(CHEMBL2141296 | IXAZOMIB CITRATE | Ixazomib | MLN2...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate measured every 5 mins for 120 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50589478(CHEMBL5187480)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human TDP1 measured by real-time oligonucleotide biosensor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318572(2-{4-[6-Bromo-2-(4-dimethylaminomethylphenyl)-3H-i...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318594(6-Bromo-2-(4-methoxyphenyl)-7-[4-(5-methyl-isoxazo...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318596(3-((4-(6-Bromo-2-(4-(4-methylpiperazin-1-yl)phenyl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant Aurora C expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318608(2-(4-(6-Chloro-7-(4-((5-methylisoxazol-3-yl)methyl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318596(3-((4-(6-Bromo-2-(4-(4-methylpiperazin-1-yl)phenyl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant Aurora B expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50463376(CHEMBL4244758)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50507151(CHEMBL4438274)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50507151(CHEMBL4438274)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human TDP1 measured by real-time oligonucleotide biosensor assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318600(4-(4-(6-Bromo-7-(4-((1-methyl-1H-imidazol-2-yl)met...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318607(2-(4-(6-Bromo-7-(4-((5-methylisoxazol-3-yl)methyl)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318599(6-Bromo-2-(4-methoxyphenyl)-7-(4-((1-methyl-1H-imi...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50507140(CHEMBL4440514)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318591(6-Bromo-7-[4-(4-chlorobenzyl)-piperazin-1-yl]-2-(4...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50224734(2-(4-(6-Chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50224734(2-(4-(6-Chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50:  42nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318569(2-(4-(6-Cyano-2-(4-(dimethylamino)phenyl)-3H-imida...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318574(2-(4-(6-Chloro-2-(4-methoxyphenyl)-3H-imidazo[4,5-...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318568(2-(4-(6-Cyclopropyl-2-(4-methoxyphenyl)-3H-imidazo...)
Affinity DataIC50:  53nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318570(2-{4-[6-Bromo-2-(4-dimethylaminophenyl)-3H-imidazo...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318586(4-(6-Bromo-7-(4-(pyridin-4-ylmethyl)piperazin-1-yl...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318606((4-(6-Chloro-7-(4-((5-methylisoxazol-3-yl)methyl)p...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50463381(CHEMBL4241424)
Affinity DataIC50:  63nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50463368(CHEMBL4250901)
Affinity DataIC50:  64nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Science

Curated by ChEMBL
LigandPNGBDBM50507150(CHEMBL4440114)
Affinity DataIC50:  68nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50318579(2-(4-(6-Chloro-2-(4-(dimethylamino)phenyl)-3H-imid...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant Aurora A expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 277 total ) | Next | Last >>
Jump to: