Compile Data Set for Download or QSAR
maximum 50k data
Found 1006 with Last Name = 'rice' and Initial = 'm'
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410903(CHEMBL207598)
Affinity DataKi:  0.5nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410898(CHEMBL205757)
Affinity DataKi:  0.510nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410901(CHEMBL206413)
Affinity DataKi:  0.650nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410899(CHEMBL383674)
Affinity DataKi:  0.720nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410904(CHEMBL377532)
Affinity DataKi:  0.720nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50069984((R)-1-((S)-2-((S)-2-(benzyloxycarbonyl)-4-methylpe...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Attenuon

Curated by ChEMBL
LigandPNGBDBM50121753(1-(5-Chloro-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin...)
Affinity DataKi:  5nMAssay Description:Binding affinity towards recombinant thymidine phosphorylase TPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410906(CHEMBL207160)
Affinity DataKi:  5.70nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015743(Acetic acid 3-[1-(3,6-dihydro-2H-pyridin-1-yl)-cyc...)
Affinity DataKi:  6nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015738(3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-phe...)
Affinity DataKi:  7nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13940(2-(3-HYDROXY-PYRIDIN-2-YL)-1H-BENZOIMIDAZOLE-5-CAR...)
Affinity DataKi:  8nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015734(1-(1-Thiophen-2-yl-cyclohexyl)-1,2,3,6-tetrahydro-...)
Affinity DataKi:  12nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13940(2-(3-HYDROXY-PYRIDIN-2-YL)-1H-BENZOIMIDAZOLE-5-CAR...)
Affinity DataKi:  17nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073987(1,1,1-Trifluoro-9-phenyl-nonan-2-one | 1,1,1-trifl...)
Affinity DataKi:  25nMAssay Description:Inhibitory concentration of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410900(CHEMBL207425)
Affinity DataKi:  32nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015741(1-[1-(3-Methoxy-phenyl)-cyclohexyl]-1,2,3,6-tetrah...)
Affinity DataKi:  33nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015732(1-(1-Phenyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridin...)
Affinity DataKi:  37nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410896(CHEMBL383122)
Affinity DataKi:  38nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13940(2-(3-HYDROXY-PYRIDIN-2-YL)-1H-BENZOIMIDAZOLE-5-CAR...)
Affinity DataKi:  43nM ΔG°:  -41.6kJ/molepH: 8.0 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410907(CHEMBL437311)
Affinity DataKi:  45nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015733(3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...)
Affinity DataKi:  56nMAssay Description:Ability to displace [3H]-TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  65nM ΔG°:  -40.6kJ/molepH: 8.0 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015735(1-(1-m-Tolyl-cyclohexyl)-1,2,3,6-tetrahydro-pyridi...)
Affinity DataKi:  81nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50069273((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...)
Affinity DataKi:  82nMAssay Description:Inhibitory concentration of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015744(1-[1-(3-Methoxymethoxy-phenyl)-cyclohexyl]-1,2,3,6...)
Affinity DataKi:  92nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073986(1,1,1-Trifluoro-8-(4-heptyl-phenyl)-octan-2-one | ...)
Affinity DataKi:  96nMAssay Description:Inhibitory constant of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073974(1,1,1-Trifluoro-8-phenyl-octan-2-one | 1,1,1-Trifl...)
Affinity DataKi:  100nMAssay Description:Inhibitory constant of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015740(1-[1-(3-Vinyl-phenyl)-cyclohexyl]-1,2,3,6-tetrahyd...)
Affinity DataKi:  114nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410902(CHEMBL205687)
Affinity DataKi:  130nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073985(1,1,1-Trifluoro-undecan-2-one | 1,1,1-trifluoround...)
Affinity DataKi:  130nMAssay Description:Inhibitory constant of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073984(1,1,1-Trifluoro-8-(3-hexyl-phenyl)-octan-2-one | C...)
Affinity DataKi:  140nMAssay Description:Inhibitory constant of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50410908(CHEMBL381931)
Affinity DataKi:  140nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073975(1,1,1-Trifluoro-tridecan-2-one | 1,1,1-trifluorotr...)
Affinity DataKi:  140nMAssay Description:Inhibitory constant of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073989(1,1,1-Trifluoro-7-phenyl-heptan-2-one | 1,1,1-Trif...)
Affinity DataKi:  170nMAssay Description:Inhibitory concentration of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  170nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073973((E)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-Tr...)
Affinity DataKi:  170nMAssay Description:Inhibitory constant of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50069276(4-Bromo-3-oxo-butyric acid (Z)-tetradec-5-enyl est...)
Affinity DataKi:  190nMpH: 9.0Assay Description:Compound was tested for inhibitory potency against Fatty-acid amide hydrolase (FAAH) at pH 9.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015731(1-[1-(3-Methylsulfanyl-phenyl)-cyclohexyl]-1,2,3,6...)
Affinity DataKi:  231nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Attenuon

Curated by ChEMBL
LigandPNGBDBM50201010(((2R,3aR,4R,6R,6aR)-4-(hydroxymethyl)-6-(5-methyl-...)
Affinity DataKi:  236nMAssay Description:Inhibition of human thymidine phosphorylase by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073981(1,1,1-Trifluoro-nonadecan-2-one | 1,1,1-trifluoron...)
Affinity DataKi:  240nMAssay Description:Inhibitory constant of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50365344(CHEMBL1956115)
Affinity DataKi:  250nMAssay Description:Inhibition of human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50069273((Z)-1,1,1-Trifluoro-nonadec-10-en-2-one | 1,1,1-tr...)
Affinity DataKi:  250nMpH: 9.0Assay Description:Compound was tested for inhibitory potency against Fatty-acid amide hydrolase (FAAH) at pH 9.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13937(2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMI...)
Affinity DataKi:  280nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015736(1-[1-(3-Fluoro-phenyl)-cyclohexyl]-1,2,3,6-tetrahy...)
Affinity DataKi:  281nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50073982(1,1,1-Trifluoro-9-(2-octyl-phenyl)-nonan-2-one | C...)
Affinity DataKi:  320nMAssay Description:Inhibitory constant of the compound against Fatty-acid amide hydrolase (FAAH) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50015739(3-[1-(3,6-Dihydro-2H-pyridin-1-yl)-cyclohexyl]-ben...)
Affinity DataKi:  324nMAssay Description:Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  330nMAssay Description:Inhibition of trypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

LigandPNGBDBM13941(APC-8249 | {amino[2-(2-hydroxy-5-nitrophenyl)-1H-1...)
Affinity DataKi:  340nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Axys Pharmaceuticals

LigandPNGBDBM13945(APC-13140 | [amino(2-{hydroxy[(3-phenoxyphenyl)met...)
Affinity DataKi:  380nM ΔG°:  -36.3kJ/molepH: 7.7 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1006 total ) | Next | Last >>
Jump to: