Compile Data Set for Download or QSAR
maximum 50k data
Found 822 with Last Name = 'sabnis' and Initial = 'rw'
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498319(US11014911, Example 144 | US11718603, Example 144)
Affinity DataKi:  0.100nMAssay Description:Inhibition of recombinant full length wild-type CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as reduction in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498320(US11014911, Example 145 | US11718603, Example 145)
Affinity DataKi:  0.120nMAssay Description:Inhibition of recombinant full length wild-type CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as reduction in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498334(US11014911, Example 159 | US11014911, Example 160 ...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of recombinant full length wild-type CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as reduction in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498332(US11014911, Example 157 | US11014911, Example 158 ...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of recombinant full length wild-type CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as reduction in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580039(CHEMBL5071355)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human full length recombinant HPK1 using 5FAM-AKRRRLSSLRACOOH as substrate preincubated for 20 mins and measured for 60 mins by microfl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580043(CHEMBL5076500)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human full length recombinant HPK1 using 5FAM-AKRRRLSSLRACOOH as substrate preincubated for 20 mins and measured for 60 mins by microfl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580040(CHEMBL5083474)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human full length recombinant HPK1 using 5FAM-AKRRRLSSLRACOOH as substrate preincubated for 20 mins and measured for 60 mins by microfl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580042(CHEMBL5075798)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human full length recombinant HPK1 using 5FAM-AKRRRLSSLRACOOH as substrate preincubated for 20 mins and measured for 60 mins by microfl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580041(CHEMBL5092129)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human full length recombinant HPK1 using 5FAM-AKRRRLSSLRACOOH as substrate preincubated for 20 mins and measured for 60 mins by microfl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50580044(CHEMBL5085639)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human full length recombinant HPK1 using 5FAM-AKRRRLSSLRACOOH as substrate preincubated for 20 mins and measured for 60 mins by microfl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498731((1S,3R)-3-(3-{[(6- methoxypyridin-3- yl)acetyl]a...)
Affinity DataKi:  0.460nMAssay Description:Inhibition of recombinant full length wild-type CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as reduction in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498707((1R,3S)-3-(3-{[(6- methoxypyridin-3- yl)acetyl]a...)
Affinity DataKi:  0.770nMAssay Description:Inhibition of recombinant full length wild-type CDK2/Cyclin E1 (unknown origin) expressed in baculovirus expression system assessed as reduction in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498332(US11014911, Example 157 | US11014911, Example 158 ...)
Affinity DataKi:  0.780nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta H350L mutant expressed in baculovirus-infected Sf21 cells assessed as reduction in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498320(US11014911, Example 145 | US11718603, Example 145)
Affinity DataKi:  0.950nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta H350L mutant expressed in baculovirus-infected Sf21 cells assessed as reduction in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498319(US11014911, Example 144 | US11718603, Example 144)
Affinity DataKi:  1.30nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta H350L mutant expressed in baculovirus-infected Sf21 cells assessed as reduction in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498707((1R,3S)-3-(3-{[(6- methoxypyridin-3- yl)acetyl]a...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta H350L mutant expressed in baculovirus-infected Sf21 cells assessed as reduction in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498334(US11014911, Example 159 | US11014911, Example 160 ...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta H350L mutant expressed in baculovirus-infected Sf21 cells assessed as reduction in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM498731((1S,3R)-3-(3-{[(6- methoxypyridin-3- yl)acetyl]a...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of N-terminal His6-tagged human recombinant GSK3beta H350L mutant expressed in baculovirus-infected Sf21 cells assessed as reduction in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574358(CHEMBL4860757)
Affinity DataIC50:  0nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 10 mins followed by tripeptide substrate addition and measured after 60 mins by fluorescence mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574359(CHEMBL4856052)
Affinity DataIC50:  0nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 10 mins followed by tripeptide substrate addition and measured after 60 mins by fluorescence mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))TBA
LigandPNGBDBM50582221(CHEMBL5090028 | US11708359, Example 60)
Affinity DataIC50:  0.00720nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574374(CHEMBL4850648 | US20230271956, Compound 87)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574375(CHEMBL4876400 | US20230271956, Compound 102)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574371(CHEMBL4867121 | US20230271956, Compound 55)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574372(CHEMBL4848186 | US20230271956, Compound 59)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574374(CHEMBL4850648 | US20230271956, Compound 87)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574371(CHEMBL4867121 | US20230271956, Compound 55)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574372(CHEMBL4848186 | US20230271956, Compound 59)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574373(CHEMBL4873965 | US20230271956, Compound 60)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574375(CHEMBL4876400 | US20230271956, Compound 102)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574373(CHEMBL4873965 | US20230271956, Compound 60)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578400(CHEMBL4862805 | US20240009175, Compound 50)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones measured after 24 hrs by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578400(CHEMBL4862805 | US20240009175, Compound 50)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578401(CHEMBL4870590 | US20240009175, Compound 57)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578402(CHEMBL4853889 | US20240009175, Compound 63)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of human recombinant ACSS2 assessed as AMP release using Coenzyme A/ATP as co-substrates by AMP Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578397(CHEMBL4855352 | US20240009175, Compound 33)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Homo sapiens)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578398(CHEMBL4859117 | US20240009175, Compound 35)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids measured after 24 hrs by scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))TBA
LigandPNGBDBM609871((rac)-(2s,4s)-2-(6-(4-(tert-Butyl)phenyl)-3-azabic...)
Affinity DataIC50:  0.0190nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))TBA
LigandPNGBDBM50582222(CHEMBL5074982 | US11708359, Example 71)
Affinity DataIC50:  0.0240nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50599226(CHEMBL5201062 | US11866405, Example 100)
Affinity DataIC50: <0.0300nMAssay Description:Inhibition of recombinant human full-length His-tagged IRAK4 expressed in baculovirus infected insect cells using KKARFSRFAGSSPSQSSMVAR as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))TBA
LigandPNGBDBM50552710(CHEMBL4749516)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))TBA
LigandPNGBDBM609880((rac)-(2s,4s)-2-(6-(4-(1-Methylcyclopropyl)phenyl)...)
Affinity DataIC50:  0.0340nMAssay Description:Inhibition of MGL activity in human HeLa cells assessed as reduction in cleaved [1,3-3H glycerol] level using [glycerol-1,3-3H]-oleoyl glycerol as su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMonoglyceride lipase(Homo sapiens (Human))TBA
LigandPNGBDBM50552709(CHEMBL4759880)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))TBA
LigandPNGBDBM50552711(CHEMBL4785835)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of MAGL (unknown origin) using 2-AG as substrate incubated for 15 mins followed by substrate addition and measured after 30 mins by mass s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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